The chemokine (C-X3-C motif) ligand 1 (CX3CL1), also named fractalkine (FKN), has been
implicated in psychiatric disorders and functions as a novel adipocytokine. However, no …

Fractalkine is one of the CX3C chemokine family, and it is widely expressed in the brain
including the hypothalamus. In the brain, fractalkine is expressed in neurons and binds to a …

OBJECTIVE Leukocyte infiltration of adipose is a critical determinant of obesity-related
metabolic diseases. Fractalkine (CX3CL1) and its receptor (CX3CR1) comprise a …

The fractalkine/CX3CR1 axis plays an important role in regulating glucose and lipid
metabolism. However, the role of fractalkine in metabolic disorders remains to be fully …

Background Fractalkine (FKN) is an inflammatory cytokine that has been shown with
increased serum levels in diabetic patients and is considered to contribute to the adipose …

Diet-induced obesity and related peripheral and central inflammation are major risk factors
for metabolic, neurological and psychiatric diseases. The chemokine fractalkine (Cx3CL1) …

The link between the kynurenine pathway and immunomodulatory molecules—fractalkine
and soluble intercellular adhesion molecule-1 (sICAM-1)—in anorexia nervosa (AN) …

The inflammatory component in obesity is now well established. The CX3CR1 gene
encodes the fractalkine (CX3CL1) receptor and has two coding single‐nucleotide …

The fractalkine (CX3CL1-CX3CR1) chemokine system is associated with obesity-related
inflammation and type 2 diabetes, but data on effects of Cx3cr1 deficiency on metabolic …

Here, we demonstrate that the fractalkine (FKN)/CX3CR1 system represents a regulatory
mechanism for pancreatic islet β cell function and insulin secretion. CX3CR1 knockout (KO) …