The hippocampus in aging and disease: from plasticity to vulnerability
T Bartsch, P Wulff - Neuroscience, 2015 - Elsevier
The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …
Structural plasticity and hippocampal function
B Leuner, E Gould - Annual review of psychology, 2010 - annualreviews.org
The hippocampus is a region of the mammalian brain that shows an impressive capacity for
structural reorganization. Preexisting neural circuits undergo modifications in dendritic …
structural reorganization. Preexisting neural circuits undergo modifications in dendritic …
Impact of neuroinflammation on hippocampal neurogenesis: relevance to aging and Alzheimer's disease
J Valero, L Bernardino, FL Cardoso… - Journal of …, 2017 - content.iospress.com
The cognitive reserve is associated with the capacity of the brain to maintain cognitive
performance in spite of being challenged by stressful degenerative insults related to aging …
performance in spite of being challenged by stressful degenerative insults related to aging …
A pathophysiological framework of hippocampal dysfunction in ageing and disease
The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …
Hippocampal plasticity during the progression of Alzheimer's disease
Neuroplasticity involves molecular and structural changes in central nervous system (CNS)
throughout life. The concept of neural organization allows for remodeling as a compensatory …
throughout life. The concept of neural organization allows for remodeling as a compensatory …
Structural plasticity of the hippocampus in neurodegenerative diseases
PDE Weerasinghe-Mudiyanselage, MJ Ang… - International journal of …, 2022 - mdpi.com
Neuroplasticity is the capacity of neural networks in the brain to alter through development
and rearrangement. It can be classified as structural and functional plasticity. The …
and rearrangement. It can be classified as structural and functional plasticity. The …
Aging, stress and the hippocampus
DB Miller, JP O'callaghan - Ageing research reviews, 2005 - Elsevier
Functional loss often occurs in many body systems (eg, endocrine, cognitive, motor) with the
passage of years, but there is great individual variation in the degree of compromise shown …
passage of years, but there is great individual variation in the degree of compromise shown …
The emerging role of the interplay among astrocytes, microglia, and neurons in the hippocampus in health and disease
D Lana, F Ugolini, D Nosi, GL Wenk… - Frontiers in aging …, 2021 - frontiersin.org
For over a century, neurons have been considered the basic functional units of the brain
while glia only elements of support. Activation of glia has been long regarded detrimental for …
while glia only elements of support. Activation of glia has been long regarded detrimental for …
The effects of aging in the hippocampus and cognitive decline
Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …
social impairments. One structure of particular interest when considering aging and …
The effects of hormones and physical exercise on hippocampal structural plasticity
The hippocampus plays an integral role in certain aspects of cognition. Hippocampal
structural plasticity and in particular adult hippocampal neurogenesis can be influenced by …
structural plasticity and in particular adult hippocampal neurogenesis can be influenced by …