Mechanisms of release of nucleotides and integration of their action as P2X-and P2Y-receptor activating molecules
ER Lazarowski, RC Boucher, TK Harden - Molecular pharmacology, 2003 - ASPET
The concept that adenine and uridine nucleotides function as extracellular signaling
molecules has been markedly expanded in the last decade. At least 15 nucleotide-activated …
molecules has been markedly expanded in the last decade. At least 15 nucleotide-activated …
[引用][C] Release, metabolism and interconversion of adenine and uridine nucleotides: implications for G protein-coupled P2 receptor agonist selectivity
TK Harden, ER Lazarowski, RC Boucher - Trends in Pharmacological …, 1997 - Elsevier
The occurrence of a physiologically relevant release of adenine nucleotides that results in
the activation of cell surface receptors was formally postulated several decades ago',?. More …
the activation of cell surface receptors was formally postulated several decades ago',?. More …
Enzymes involved in metabolism of extracellular nucleotides and nucleosides: functional implications and measurement of activities
GG Yegutkin - Critical reviews in biochemistry and molecular …, 2014 - Taylor & Francis
Extracellular nucleotides and nucleosides mediate diverse signaling effects in virtually all
organs and tissues. Most models of purinergic signaling depend on functional interactions …
organs and tissues. Most models of purinergic signaling depend on functional interactions …
Nucleotides as extracellular signalling molecules
ZP Chen, A Levy, SL Lightman - Journal of neuroendocrinology, 1995 - Wiley Online Library
There is now wide acceptance that ATP and other nucleotides are ubiquitous extracellular
chemical messengers. ATP and diadenosine polyphosphates can be released from …
chemical messengers. ATP and diadenosine polyphosphates can be released from …
Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide …
ER Lazarowski, RC Boucher, TK Harden - Journal of Biological Chemistry, 2000 - ASBMB
Nucleotides are important extracellular signaling molecules. At least five mammalian P2Y
receptors exist that are specifically activated by ATP, UTP, ADP, or UDP. Although the …
receptors exist that are specifically activated by ATP, UTP, ADP, or UDP. Although the …
Advances in signalling by extracellular nucleotides: the role and transduction mechanisms of P2Y receptors
D Communi, R Janssens, N Suarez-Huerta, B Robaye… - Cellular signalling, 2000 - Elsevier
Nucleotides are ubiquitous intercellular messengers whose actions are mediated by specific
receptors. Since the first clonings in 1993, it is known that nucleotide receptors belong to two …
receptors. Since the first clonings in 1993, it is known that nucleotide receptors belong to two …
[PDF][PDF] Extracellular metabolism of ATP and other nucleotides.
H Zimmermann - Naunyn-Schmiedeberg's archives of pharmacology, 2000 - academia.edu
Within the past 10 years the field of signaling via extracellular nucleotides has witnessed a
breath-taking expansion. Molecular cloning of receptors and physiological and …
breath-taking expansion. Molecular cloning of receptors and physiological and …
Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides
GR Dubyak, C El-Moatassim - American Journal of …, 1993 - journals.physiology.org
Extracellular ATP, at micromolar concentrations, induces significant functional changes in a
wide variety of cells and tissues. ATP can be released from the cytosol of damaged cells or …
wide variety of cells and tissues. ATP can be released from the cytosol of damaged cells or …
Extracellular nucleotides and nucleosides as signalling molecules
AL Giuliani, AC Sarti, F Di Virgilio - Immunology letters, 2019 - Elsevier
Extracellular nucleotides, mainly ATP, but also ADP, UTP, UDP and UDP-sugars,
adenosine, and adenine base participate in the “purinergic signalling” pathway, an …
adenosine, and adenine base participate in the “purinergic signalling” pathway, an …
P2 receptors: intracellular signaling
P2 receptors for extracellular nucleotides are divided into two categories: the ion channel
receptors (P2X) and the G-protein-coupled receptors (P2Y). For the P2X receptors, signal …
receptors (P2X) and the G-protein-coupled receptors (P2Y). For the P2X receptors, signal …
相关搜索
- release of nucleotides activating molecules
- release of nucleotides p2y receptor
- p2y receptor activating molecules
- p2y receptors transduction mechanisms
- constitutive release ecto nucleotide
- transduction mechanisms extracellular nucleotides
- mechanisms of release activating molecules
- mechanisms of release p2y receptor
- p2y receptors extracellular nucleotides
- constitutive release nucleotide concentrations