To improve glioma targeting delivery efficiency and to monitor drug delivery and treatment
outcome, a novel tumor microenvironment sensitive size-shrinkable theranostic system was …

Nanocarriers are widely used for delivering drugs to tumors and are progressing in a stable
trend. The enhanced permeability and retention (EPR) effect has been a key rationale for the …

Glioma is still hard to be treated due to their complex microenvironment. In this study, a gold
nanoparticle-based delivery system was developed. The system, An-PEG-DOX-AuNPs, was …

Glioblastoma (GBM), one of the most lethal cancers, remains as a hard task to handle. The
major hurdle of nanostructured therapeutic agents comes from the limited retention at the …

Low permeability across the blood–brain tumor barrier (BTB) and poor penetration into the
glioma parenchyma represent key obstacles for anti-glioblastoma drug delivery. In this …

Abstract cRGD-directed, NIR-responsive and robust AuNR/PEG–PCL hybrid nanoparticles
(cRGD-HNs) were designed and developed for targeted chemotherapy of human glioma …

Advances in active targeting drug delivery system (DDS) have revolutionized glioma
diagnosis and therapy. However, the lack of the sufficient targets on glioma cells and limited …

Tumor angiogenesis is a hallmark of tumor growth and metastasis, and inhibition of tumor
angiogenesis is an effective strategy for tumor therapy. The high expression levels of …

Despite the great achievements that nanomedicines have obtained so far, deep penetration
of nanomedicines into tumors is still a major challenge in tumor treatment. The enhanced …

Dual-modal imaging probes based on fluorescence (FL) and magnetic resonance (MR)
modalities have attracted great attention due to their ability to combine the target specificity …