Animal models of chronic obstructive pulmonary disease

M Fricker, A Deane, PM Hansbro - Expert opinion on drug …, 2014 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is a leading global cause of
mortality and chronic morbidity. Inhalation of cigarette smoke is the principal risk factor for …

Preclinical murine models of chronic obstructive pulmonary disease

R Vlahos, S Bozinovski - European journal of pharmacology, 2015 - Elsevier
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a major incurable global health
burden and is the 4th leading cause of death worldwide. It is believed that an exaggerated …

Modelling COPD in mice

R Vlahos, S Bozinovski, RC Gualano, M Ernst… - Pulmonary …, 2006 - Elsevier
Chronic obstructive pulmonary disease (COPD) is characterised by persistent airflow
limitation, neutrophilic inflammation, macrophage accumulation, and the production of …

Recent advances in pre-clinical mouse models of COPD

R Vlahos, S Bozinovski - Clinical science, 2014 - portlandpress.com
COPD (chronic obstructive pulmonary disease) is a major incurable global health burden
and will become the third largest cause of death in the world by 2020. It is currently believed …

Animal models of COPD: barriers, successes, and challenges

JL Wright, A Churg - Pulmonary pharmacology & therapeutics, 2008 - Elsevier
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Animal models of chronic obstructive pulmonary disease

PA Dawkins, RA Stockley - Thorax, 2001 - thorax.bmj.com
Chronic obstructive pulmonary disease (COPD) is the fifth leading cause of death in the UK,
1 causing 26 000 deaths and 240 000 hospital admissions and costing the NHS£ 486 …

[HTML][HTML] Animal models reflecting chronic obstructive pulmonary disease and related respiratory disorders: translating pre-clinical data into clinical relevance

L Tanner, AB Single - Journal of innate immunity, 2020 - karger.com
Chronic obstructive pulmonary disease (COPD) affects the lives of an ever-growing number
of people worldwide. The lack of understanding surrounding the pathophysiology of the …

Animal models of cigarette smoke-induced chronic obstructive pulmonary disease

JL Wright, A Churg - Expert review of respiratory medicine, 2010 - Taylor & Francis
Chronic exposure of laboratory animals to cigarette smoke reproduces many of the
anatomic/physiologic lesions (emphysema, small-airway remodeling and pulmonary …

Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD)

P Upadhyay, CW Wu, A Pham, AA Zeki… - Journal of Toxicology …, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide, and its global health burden is increasing. COPD is characterized by …

Animal models of COPD: W hat do they tell us?

B Jones, C Donovan, G Liu, HM Gomez… - …, 2017 - Wiley Online Library
ABSTRACT COPD is a major cause of global mortality and morbidity but current treatments
are poorly effective. This is because the underlying mechanisms that drive the development …