Long non‑coding RNA GAS5 regulates myocardial ischemia‑reperfusion injury through the PI3K/AKT apoptosis pathway by sponging miR‑532‑5p

Y Han, N Wu, F Xia, S Liu, D Jia - … Journal of Molecular …, 2020 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) have been revealed to have a marked effect in
cardiovascular diseases, including during cardiac development, cardiac hypertrophy …

[HTML][HTML] Silence of LncRNA GAS5 protects cardiomyocytes H9c2 against hypoxic injury via sponging miR-142-5p

J Du, ST Yang, J Liu, KX Zhang, JY Leng - Molecules and cells, 2019 - Elsevier
The regulatory role of long noncoding RNA (lncRNA) growth arrest-specific transcript 5
(GAS5) in both cancerous and noncancerous cells have been widely reported. This study …

[PDF][PDF] Effect of lncRNA GAS5 on rats with acute myocardial infarction through regulating miR-21.

JC Zhang, L Xia, Y Jiang, DQ Wu… - European Review for …, 2019 - europeanreview.org
OBJECTIVE: The aim of this study was to investigate the effect of long non-coding
ribonucleic acid (lncRNA) growth arrest specific 5 (GAS5) on acute myocardial infarction …

lncRNA GAS5 regulates myocardial infarction by targeting the miR‐525‐5p/CALM2 axis

Y Zhang, Y Hou, F Gao, J Xiao, C Li… - Journal of cellular …, 2019 - Wiley Online Library
Long noncoding RNAs (lncRNAs) play critical roles in the pathogenesis of cardiovascular
diseases, especially in myocardial infarction (MI). However, the underlying molecular …

Down‐regulation of GAS5 ameliorates myocardial ischaemia/reperfusion injury via the miR‐335/ROCK1/AKT/GSK‐3β axis

N Wu, X Zhang, Y Bao, H Yu, D Jia… - Journal of Cellular and …, 2019 - Wiley Online Library
Growth arrest‐specific transcript 5 (GAS5), along non‐coding RNA (LncRNA), is highly
expressed in hypoxia/reoxygenation (H/R)‐cardiomyocytes and promotes H/R‐induced …

LncRNA GAS5 exacerbates myocardial ischemia-reperfusion injury through regulating serpina3 by targeting miR-137

Z Liu, L Hou, Y Liu, J Gong - International …, 2020 - internationaljournalofcardiology.com
We carefully read with interest the recent article by Zhao et al.[1] concerning “Circulating
Serpina3 levels predict the major adverse cardiac events in patients with myocardial …

LncRNA GAS5 upregulates miR-214 through methylation to participate in cell apoptosis of sepsis

M Li, Z Zhang, B Liu, L Chen… - Archives of physiology and …, 2022 - Taylor & Francis
It has been reported that lncRNA GAS5 can inhibit LPS-induced inflammation, indicating its
involvement in sepsis. We observed the downregulation of GAS5 in plasma of sepsis …

LncRNA-GAS5 regulates PDCD4 expression and mediates myocardial infarction-induced cardiomyocytes apoptosis via targeting MiR-21

XH Zhou, HX Chai, M Bai, Z Zhang - Cell Cycle, 2020 - Taylor & Francis
The present study was designed to investigate whether and how lncRNA-GAS5 regulates
cardiomyocyte apoptosis in MI. MI rat model was established by the left anterior descending …

Long-chain noncoding RNA-GAS5/hsa-miR-138-5p attenuates high glucose-induced cardiomyocyte damage by targeting CYP11B2

X Zhuo, K Bai, Y Wang, P Liu, W Xi, J She… - Bioscience …, 2021 - portlandpress.com
Objective: Diabetic cardiomyopathy (DCM) is one of the complications experienced by
patients with diabetes. In recent years, long noncoding RNAs (lncRNAs) have been …

LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR

Y Xu, H Fang, Q Xu, C Xu, L Yang, C Huang - Cell Cycle, 2020 - Taylor & Francis
Long noncoding RNA GAS5 is down-regulated in cardiomyocytes in diabetic
cardiomyopathy (DCM). Here, we studied the involvement of GAS5 in DCM by analyzing its …