[HTML][HTML] Cancer cachexia: impact, mechanisms and emerging treatments

VC Vaughan, P Martin, PA Lewandowski - Journal of cachexia, sarcopenia …, 2013 - Springer
Many forms of cancer present with a complex metabolic profile characterised by loss of lean
body mass known as cancer cachexia. The physical impact of cachexia contributes to …

[HTML][HTML] Cancer cachexia, mechanism and treatment

T Aoyagi, KP Terracina, A Raza… - World journal of …, 2015 - ncbi.nlm.nih.gov
It is estimated that half of all patients with cancer eventually develop a syndrome of
cachexia, with anorexia and a progressive loss of adipose tissue and skeletal muscle mass …

The 2011 ESPEN Arvid Wretlind lecture: cancer cachexia: the potential impact of translational research on patient-focused outcomes

KCH Fearon - Clinical nutrition, 2012 - Elsevier
Cancer cachexia is a multifactorial syndrome characterised by loss of skeletal muscle that
cannot be fully reversed by conventional nutritional support. Uncertainty continues as to its …

[HTML][HTML] Cancer cachexia and related metabolic dysfunction

GWP Fonseca, J Farkas, E Dora… - International journal of …, 2020 - mdpi.com
Cancer cachexia is a complex multifactorial syndrome marked by a continuous depletion of
skeletal muscle mass associated, in some cases, with a reduction in fat mass. It is …

[HTML][HTML] Cancer cachexia: mechanisms and clinical implications

CL Donohoe, AM Ryan, JV Reynolds - … research and practice, 2011 - hindawi.com
Cachexia is a multifactorial process of skeletal muscle and adipose tissue atrophy resulting
in progressive weight loss. It is associated with poor quality of life, poor physical function …

Cancer-associated cachexia

VE Baracos, L Martin, M Korc, DC Guttridge… - Nature reviews Disease …, 2018 - nature.com
Cancer-associated cachexia is a disorder characterized by loss of body weight with specific
losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination …

Cancer cachexia: rationale for the MENAC (Multimodal—Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial

TS Solheim, BJA Laird, TR Balstad, A Bye… - BMJ supportive & …, 2018 - spcare.bmj.com
Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal
muscle mass that cannot be fully reversed by conventional nutritional support alone …

Mechanisms and treatment of cancer cachexia

JM Argilés, FJ López-Soriano, S Busquets - Nutrition, metabolism and …, 2013 - Elsevier
According to a recent consensus, cachexia is a complex metabolic syndrome associated
with underlying illness and characterised by loss of muscle with or without loss of fat mass …

[HTML][HTML] Cancer cachexia: traditional therapies and novel molecular mechanism-based approaches to treatment

NB Kumar, A Kazi, T Smith, T Crocker, D Yu… - … treatment options in …, 2010 - Springer
Opinion statement The complex syndrome of cancer cachexia (CC) that occurs in 50% to
80% cancer patients has been identified as an independent predictor of shorter survival and …

The pathophysiology and treatment of cancer cachexia

MD Barber - Nutrition in clinical practice, 2002 - Wiley Online Library
Cachexia in cancer patients is a major cause of morbidity and mortality. The syndrome of
cachexia seems to be a facet of the inflammatory response to injury. This proinflammatory …