[HTML][HTML] Porphyromonas gingivalis bypasses epithelial barrier and modulates fibroblastic inflammatory response in an in vitro 3D spheroid model

IM Bugueno, F Batool, L Keller, S Kuchler-Bopp… - Scientific Reports, 2018 - nature.com
Porphyromonas gingivalis-induced inflammatory effects are mostly investigated in
monolayer cultured cells. The aim of this study was to develop a 3D spheroid model of …

[HTML][HTML] Characterisation and optimisation of organotypic oral mucosal models to study Porphyromonas gingivalis invasion

A Pinnock, C Murdoch, K Moharamzadeh… - Microbes and …, 2014 - Elsevier
Porphyromonas gingivalis is a Gram-negative, keystone pathogen in periodontitis that leads
to tissue destruction and ultimately tooth loss. The organism is able to infect oral epithelial …

Dynamic analysis of Porphyromonas gingivalis invasion into blood capillaries during the infection process in host tissues using a vascularized three-dimensional …

N Sasaki, H Takeuchi, S Kitano, S Irie, A Amano… - Biomaterials …, 2021 - pubs.rsc.org
Porphyromonas gingivalis, the pathogen of periodontal disease, is thought to be involved in
various diseases throughout the body via gingival tissue blood capillaries. However, the …

[HTML][HTML] Topical application of Porphyromonas gingivalis into the gingival pocket in mice leads to chronic‑active infection, periodontitis and systemic inflammation

S Kim, Y Bando, C Chang, J Kwon… - International …, 2022 - spandidos-publications.com
Porphyromonas gingivalis (Pg), one of the 'red‑complex'perio‑pathogens known to play a
critical role in the development of periodontitis, has been used in various animal models to …

Dual lifestyle of Porphyromonas gingivalis in biofilm and gingival cells

A Sakanaka, H Takeuchi, M Kuboniwa, A Amano - Microbial pathogenesis, 2016 - Elsevier
Porphyromonas gingivalis is deeply involved in the pathogenesis of marginal periodontitis,
and recent findings have consolidated its role as an important and unique pathogen. This …

Porphyromonas Gingivalis and Dextran Sulfate Sodium Induce Periodontitis Through the Disruption of Physical Barriers in Mice

YS Choi, YC Kim, AR Jo, S Ji, KT Koo… - European journal of …, 2013 - journals.sagepub.com
Periodontitis is a chronic inflammatory disease caused by the interaction of plaque-
associated bacteria with host cells. Gingival epithelial barriers provide the first line of …

[HTML][HTML] Human primary epithelial cells acquire an epithelial-mesenchymal-transition phenotype during long-term infection by the oral opportunistic pathogen …

J Lee, JAS Roberts, KR Atanasova… - Frontiers in cellular …, 2017 - frontiersin.org
Porphyromonas gingivalis is a host-adapted oral pathogen associated with chronic
periodontitis that successfully survives and persists in the oral epithelium. Recent studies …

[HTML][HTML] Comparative gene expression analysis of Porphyromonas gingivalis ATCC 33277 in planktonic and biofilms states

P Romero-Lastra, MC Sanchez, H Ribeiro-Vidal… - PloS one, 2017 - journals.plos.org
Background and objective Porphyromonas gingivalis is a keystone pathogen in the onset
and progression of periodontitis. Its pathogenicity has been related to its presence and …

Complex intratissue microbiota forms biofilms in periodontal lesions

K Baek, S Ji, Y Choi - Journal of Dental Research, 2018 - journals.sagepub.com
Periodontitis is caused by dysbiotic subgingival bacterial communities that may lead to
increased bacterial invasion into gingival tissues. Although shifts in community structures …

[HTML][HTML] Candida albicans Shields the Periodontal Killer Porphyromonas gingivalis from Recognition by the Host Immune System and Supports the Bacterial …

D Bartnicka, M Gonzalez-Gonzalez, J Sykut… - International Journal of …, 2020 - mdpi.com
Candida albicans is a pathogenic fungus capable of switching its morphology between
yeast-like cells and filamentous hyphae and can associate with bacteria to form mixed …