Since the turn of the century, advances in targeted therapy and immunotherapy have
revolutionized the treatment of cancer. Although these approaches have far outperformed …

The recent impact of cancer immunotherapies has firmly established the ability and
importance of the immune system to fight malignancies. However, the intimate interaction …

The immune system plays a key role in the interactions between host and tumor. Immune
selection pressure is a driving force behind the sculpting and evolution of malignant cancer …

Cancer immunotherapy has fundamentally altered cancer treatment; however, its efficacy is
limited to a subset of patients in most clinical settings. The immune system plays a key role …

Immunogenic-and immune-therapies have become hot spots in the treatment of cancer.
Although promising, these strategies are frequently associated with innate or acquired …

An increased understanding of the interactions between the immune system and tumors has
opened the door to immunotherapy for cancer patients. Despite some success with …

Immune response has been shown to play an important role in defining patient prognosis
and response to cancer treatment. Tumor-induced immunosuppression encouraged the …

The host immune response is a potent defense mechanism against cancer development
and progression. To survive, cancer cells must develop mechanisms to evade the immune …

Cancer immunotherapy, particularly immune checkpoint inhibitors, has opened a new
avenue for cancer treatment following the durable clinical benefits. Despite the clinical …

Decades of research into the molecular mechanisms of cancer and the development of
novel therapeutics have yielded a number of remarkable successes. However, our ability to …