DETA-NONOate, a nitric oxide (NO) donor, induced cytostasis in the human breast cancer
cells MDA-MB-231, and the cells were arrested in the G1 phase of the cell cycle. This …

Cell-mediated antitumor effects have, in part, been attributed to the production of NO.
Compounds which generate NO might, therefore, be useful in attenuating the growth of …

Nitric oxide (NO) is a messenger molecule with various biological activities including DNA
damage. In the present study, we examined the influence of endogenously produced NO on …

Nitric oxide (NO), a multifaceted signaling molecule, regulates a wide array of cell functions,
including proliferation, differentiation, cytostasis, and apoptosis, which depend on the cell …

Using clonal derivatives of spontaneous mammary tumours in C3H/HeJ mice, we had earlier
shown that tumour‐derived nitric oxide (NO), resulting from endothelial type (e) NO synthase …

Nitric oxide (NO) in nanomolar (nmol/L) concentrations is consistently detected in tumor
microenvironment and has been found to promote tumorigenesis. The mechanism by which …

Nitric oxide (NO) has potent antiproliferative properties. In previous work we have shown
that NO inhibits growth, induces differentiation and modulates gene expression in acute …

Thiol antioxidants, including N-acetyl-l-cysteine (NAC), are widely used as modulators of the
intracellular redox state. We investigated the hypothesis that NAC-induced reactive oxygen …

Nitric oxide (NO) is a potent bioactive molecule produced in the presence of NO synthase
(NOS) enzymes, which mediates numerous physiological functions under constitutive …

Nitric oxide (NO) is generated by a family of isoenzymes named nitric oxide synthases
(NOS) which includes a cytokine-inducible form, NOSII. NO is a free radical known to inhibit …