What Are the Roles of Oligodendrocyte Precursor Cells in Normal and Pathologic Conditions?
E Benarroch - Neurology, 2023 - AAN Enterprises
Adult oligodendrocyte precursor (or progenitor) cells (OPCs) are the most proliferative cells
in the CNS and constitute approximately 10% of cells in the human brain. 1, 2 Whereas their …
in the CNS and constitute approximately 10% of cells in the human brain. 1, 2 Whereas their …
Many roles for oligodendrocyte precursor cells in physiology and pathology
A Nishiyama, DR Serwanski, F Pfeiffer - Neuropathology, 2021 - Wiley Online Library
Oligodendrocyte precursor cells (OPCs) are a fourth resident glial cell population in the
mammalian central nervous system. They are evenly distributed throughout the gray and …
mammalian central nervous system. They are evenly distributed throughout the gray and …
The oligodendrocyte precursor cell in health and disease
JM Levine, R Reynolds, JW Fawcett - Trends in neurosciences, 2001 - cell.com
Adult oligodendrocyte precursor cells (OPCs) make up around 5–8% of the glial cell
population in the CNS. Their function in the undamaged CNS is largely unknown, but their …
population in the CNS. Their function in the undamaged CNS is largely unknown, but their …
A matter of state: diversity in oligodendrocyte lineage cells
Y Kamen, H Pivonkova, KA Evans… - The …, 2022 - journals.sagepub.com
Oligodendrocyte precursor cells (OPCs) give rise to oligodendrocytes which myelinate
axons in the central nervous system. Although classically thought to be a homogeneous …
axons in the central nervous system. Although classically thought to be a homogeneous …
Heterogeneity of oligodendrocyte progenitor cells in adult human brain
SY Leong, VTS Rao, JM Bin, P Gris… - Annals of clinical …, 2014 - Wiley Online Library
Objective Remyelination in multiple sclerosis has been attributed to the presence of
oligodendrocyte progenitor cells (OPC s) in brain parenchyma. However, the precise identity …
oligodendrocyte progenitor cells (OPC s) in brain parenchyma. However, the precise identity …
Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune function
Oligodendrocyte precursor cells (OPCs) are not merely a transitory progenitor cell type, but
rather a distinct and heterogeneous population of glia with various functions in the …
rather a distinct and heterogeneous population of glia with various functions in the …
Oligodendrocyte progenitors: adult stem cells of the central nervous system?
AH Crawford, JH Stockley, RB Tripathi… - Experimental …, 2014 - Elsevier
Oligodendrocyte progenitors (OPs) are a major proliferating cell population within the adult
CNS. In response to myelin loss or increasing demand, OPs have the capacity to …
CNS. In response to myelin loss or increasing demand, OPs have the capacity to …
Oligodendrocytes in development, myelin generation and beyond
S Kuhn, L Gritti, D Crooks, Y Dombrowski - Cells, 2019 - mdpi.com
Oligodendrocytes are the myelinating cells of the central nervous system (CNS) that are
generated from oligodendrocyte progenitor cells (OPC). OPC are distributed throughout the …
generated from oligodendrocyte progenitor cells (OPC). OPC are distributed throughout the …
Myelination-independent functions of oligodendrocyte precursor cells in health and disease
Oligodendrocyte precursor cells (OPCs) are a population of tissue-resident glial cells found
throughout the CNS, constituting approximately 5% of all CNS cells and persisting from …
throughout the CNS, constituting approximately 5% of all CNS cells and persisting from …
Oligodendrocyte progenitor cells become regionally diverse and heterogeneous with age
SO Spitzer, S Sitnikov, Y Kamen, KA Evans… - Neuron, 2019 - cell.com
Oligodendrocyte progenitor cells (OPCs), which differentiate into myelinating
oligodendrocytes during CNS development, are the main proliferative cells in the adult …
oligodendrocytes during CNS development, are the main proliferative cells in the adult …