The obesity epidemic is a critical public health problem closely associated with the
development of metabolic disease. In obesity there is excess white adipose tissue, a …

The visceral adipose tissue (VAT) has been shown to play an important role in various
biological functions. It is a storage depot for nutrients and it is an important endocrine organ …

Objective Surgical manipulations of adipose tissue by removal, or partial lipectomy, have
demonstrated body fat compensation and recovered body weight, suggesting that the body …

The role of adipose tissue, or fat, in the development and treatment of metabolic disease is
the subject of this issue's Select. A cluster of new studies in mice suggest that dysregulation …

Obesity has reached epidemic proportions, leading to an increase of associated pathologies
such as insulin resistance, cardiovascular disease, some types of cancer and type 2 …

Obesity is a chronic disease that increases susceptibility to various diseases, particularly
cardiovascular dysfunction, type 2 diabetes, and some types of cancer. In this review, we …

It is well established that although adults tend to remain relatively weight stable over long
periods of time, there is a tendency toward a 1-kilogram per year weight gain between the …

Obesity is an escalating world problem that contributes to the complexity and cost of
treatment of metabolic disorders. Obesity is the result of increased storage of energy in the …

Evolution has given rise to a variety of ways to store energy ranging from small intracellular
lipid droplets to specialized tissue called adipose, which is composed of adipocytes …

Surgical removal of body fat (partial lipectomy) is a means of directly reducing fat such that
metabolic and behavioral responses can be readily attributed to the lipid deficit. If total body …