Activation of receptors for a wide variety of hormones and neurotransmitters leads to an
increase in the intracellular level of calcium. Much of this calcium is released from …

Several hormones and neurotransmitters raise the cytosolic free Ca2+ concentration by
stimulating the influx of Ca2+ and/or by mobilizing stored Ca2+ (refs 1, 2). However, the link …

Many receptors for hormones, neurotransmitters and other signals cause hydrolysis of
phosphatidylinositol 4, 5-bisphosphate (PtdIns (4, 5) P2) and effect a rise in cytosolic Ca2+ …

The increase in cytosolic [Ca2+] induced by Ca-mobilizing hormones in liver is mainly due to
release of Ca from intracellular stores1–7. For Ca to be released from internal sites a …

MANY hormones, neurotransmitters and growth factors evoke in their target cells oscillations
in the free internal Ca2+ concentration ([Ca2+] i)(ref. 1). In electrically non-excitable cells …

The enhanced metabolism of phosphoinositides, which is associated with a wide variety of
stimuli and physiological responses, has been studied intensively. Berridge and his …

Several receptors for neurotransmitters, hormones and growth factors cause accelerated
phosphodiesteratic breakdown of poly-phosphoinositides when activated1, 2. One of the …

Abstract INOSITOL 1, 4, 5-trisphosphate (Ins (1, 4, 5) P3), a second messenger molecule
involved in actions of neurotransmitters, hormones and growth factors, releases calcium …

Abstract LOW concentrations of inositol 1, 4, 5-trisphosphate (InsP3) evoke a very rapid
mobilization of intracellular Ca2+ stores in many cell types, which can be followed by a …

Many neurotransmitters, hormones and growth factors act at membrane receptors to
stimulate the phosphodiesteratic hydrolysis of phosphatidyl-inositol 4, 5-bisphosphate …