Dopamine neurons project to the striatum to control movement, cognition, and motivation via
slower volume transmission as well as faster dopamine, glutamate, and GABA synaptic …

The striatum and its ventral extension, the nucleus accumbens, are involved in behaviors as
diverse as motor planning, drug seeking, and learning. Invariably, these striatally mediated …

Dopamine is a neurotransmitter which has defied interpretation in part because of the
multiplicity of its actions. In this chapter we focus on dopamine's actions in the striatum. We …

Striatal dopamine governs a wide range of behavioral functions, yet local dopamine
concentrations can be dissociated from somatic activity. Here, we discuss how dopamine's …

In recent years, the population of neurons in the ventral tegmental area (VTA) and substantia
nigra (SN) has been examined at multiple levels. The results indicate that the projections …

Midbrain dopamine neurons fire in bursts conveying salient information. Bursts are
associated with pauses in tonic firing of striatal cholinergic interneurons. Although the …

Dopamine input to the striatum is required for voluntary motor movement, behavioral
reinforcement, and responses to drugs of abuse. It is speculated that these functions are …

Nicola, Saleem M. and Robert C. Malenka. Modulation of synaptic transmission by
dopamine and norepinephrine in ventral but not dorsal striatum. J. Neurophysiol. 79: 1768 …

The balance of dopamine and acetylcholine in the dorsal striatum is critical for motor and
learning functions. Midbrain dopamine cells and local cholinergic interneurons (ChIs) …

The dopaminergic system exerts dynamic modulation of glutamatergic afferent drive that is
dependent on the temporal pattern of the dopaminergic input and the subtypes of striatal …