Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth
Immediately after birth, newborn babies experience rapid colonization by microorganisms
from their mothers and the surrounding environment. Diseases in childhood and later in life …
from their mothers and the surrounding environment. Diseases in childhood and later in life …
Multi-kingdom ecological drivers of microbiota assembly in preterm infants
The gut microbiota of preterm infants develops predictably,,,,,–, with pioneer species
colonizing the gut after birth, followed by an ordered succession of microorganisms. The gut …
colonizing the gut after birth, followed by an ordered succession of microorganisms. The gut …
Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life
M Reyman, MA van Houten, D van Baarle… - Nature …, 2019 - nature.com
The early-life microbiome appears to be affected by mode of delivery, but this effect may
depend on intrapartum antibiotic exposure. Here, we assess the effect of delivery mode on …
depend on intrapartum antibiotic exposure. Here, we assess the effect of delivery mode on …
Viable bacterial colonization is highly limited in the human intestine in utero
E Rackaityte, J Halkias, EM Fukui, VF Mendoza… - Nature medicine, 2020 - nature.com
Mucosal immunity develops in the human fetal intestine by 11–14 weeks of gestation, yet
whether viable microbes exist in utero and interact with the intestinal immune system is …
whether viable microbes exist in utero and interact with the intestinal immune system is …
Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery
Human microbial communities are characterized by their taxonomic, metagenomic and
metabolic diversity, which varies by distinct body sites and influences human physiology …
metabolic diversity, which varies by distinct body sites and influences human physiology …
Delivery mode affects stability of early infant gut microbiota
CM Mitchell, C Mazzoni, L Hogstrom, A Bryant… - Cell Reports …, 2020 - cell.com
Mode of delivery strongly influences the early infant gut microbiome. Children born by
cesarean section (C-section) lack Bacteroides species until 6–18 months of age. One …
cesarean section (C-section) lack Bacteroides species until 6–18 months of age. One …
Early life colonization of the human gut: microbes matter everywhere
Highlights•The intestinal microbiota follows a common successional pattern in early
life.•Particular bacterial taxa are mainly transmitted from the mother to the infant after …
life.•Particular bacterial taxa are mainly transmitted from the mother to the infant after …
Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer
MG Dominguez-Bello, KM De Jesus-Laboy, N Shen… - Nature medicine, 2016 - nature.com
Exposure of newborns to the maternal vaginal microbiota is interrupted with cesarean
birthing. Babies delivered by cesarean section (C-section) acquire a microbiota that differs …
birthing. Babies delivered by cesarean section (C-section) acquire a microbiota that differs …
The maternal microbiota drives early postnatal innate immune development
M Gomez de Agüero, SC Ganal-Vonarburg, T Fuhrer… - Science, 2016 - science.org
Postnatal colonization of the body with microbes is assumed to be the main stimulus to
postnatal immune development. By transiently colonizing pregnant female mice, we show …
postnatal immune development. By transiently colonizing pregnant female mice, we show …
Biphasic assembly of the murine intestinal microbiota during early development
IG Pantoja-Feliciano, JC Clemente… - The ISME …, 2013 - academic.oup.com
The birth canal provides mammals with a primary maternal inoculum, which develops into
distinctive body site-specific microbial communities post-natally. We characterized the distal …
distinctive body site-specific microbial communities post-natally. We characterized the distal …