Gastrointestinal (GI) cancers, especially gastric cancer and colorectal cancer (CRC),
represent a major global health burden. A large population of microorganisms residing in …

Nuclear factor kappa B (NF-κB) has an established role in the regulation of innate immunity
and inflammation. NF-κB is also involved in critical mechanisms connecting inflammation …

Chronic inflammation is linked to the development of multiple cancers, including those of the
colon. Inflammation in the gut induces carcinogenic mutagenesis and promotes colorectal …

Polymorphisms in NFKB1 that diminish its expression have been linked to human
inflammatory diseases and increased risk for epithelial cancers. The underlying …

Patients with chronic inflammatory bowel diseases are at an increased risk of developing
colitis-associated cancer (CAC). Chronic inflammation positively correlates with …

Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …

Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the world.
Besides genetic causes, colonic inflammation is one of the major risk factors for CRC …

Colitis-associated cancer is the subtype of colorectal cancer that is associated with
inflammatory bowel diseases including ulcerative colitis and Crohn's disease. Colorectal …

Recently, an unprecedented effort has been directed at understanding the interplay between
chronic inflammation and development of cancer, with the case of inflammatory bowel …

Gastric cancer is a leading cause of cancer death worldwide. Diet, obesity, smoking and
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …