The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke
CJ Cunningham, E Redondo-Castro… - Journal of Cerebral …, 2018 - journals.sagepub.com
Mesenchymal stem cells (MSCs) hold great potential as a regenerative therapy for stroke,
leading to increased repair and functional recovery in animal models of cerebral ischaemia …
leading to increased repair and functional recovery in animal models of cerebral ischaemia …
Paracrine effects of mesenchymal stem cells in ischemic stroke: Opportunities and challenges
It is well acknowledged that neuroprotective effects of transplanted mesenchymal stem cells
(MSCs) in ischemic stroke are attributed to their paracrine-mediated actions or bystander …
(MSCs) in ischemic stroke are attributed to their paracrine-mediated actions or bystander …
Mesenchymal stem cell-based therapy for stroke: current understanding and challenges
W Li, L Shi, B Hu, Y Hong, H Zhang, X Li… - Frontiers in Cellular …, 2021 - frontiersin.org
Stroke, the most prevalent cerebrovascular disease, causes serious loss of neurological
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …
[HTML][HTML] The stem cell secretome and its role in brain repair
Compelling evidence exists that non-haematopoietic stem cells, including mesenchymal
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
Microvesicles from brain-extract—treated mesenchymal stem cells improve neurological functions in a rat model of ischemic stroke
Transplantation of mesenchymal stem cells (MSCs) was reported to improve functional
outcomes in a rat model of ischemic stroke, and subsequent studies suggest that MSC …
outcomes in a rat model of ischemic stroke, and subsequent studies suggest that MSC …
Extracellular vesicles in mesenchymal stromal cells: A novel therapeutic strategy for stroke
Y Li, Q Cheng, G Hu, T Deng… - Experimental and …, 2018 - spandidos-publications.com
A stroke is a focal cerebral insult that frequently causes severe neurological deficit and
mortality. Recent studies have demonstrated that multipotent mesenchymal stromal cells …
mortality. Recent studies have demonstrated that multipotent mesenchymal stromal cells …
Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …
[HTML][HTML] Mesenchymal stromal cell secretome for traumatic brain injury: Focus on immunomodulatory action
F Pischiutta, E Caruso, H Cavaleiro, AJ Salgado… - Experimental …, 2022 - Elsevier
The severity and long-term consequences of brain damage in traumatic brain injured (TBI)
patients urgently calls for better neuroprotective/neuroreparative strategies for this …
patients urgently calls for better neuroprotective/neuroreparative strategies for this …
The secretome of mesenchymal stem cells: potential implications for neuroregeneration
G Paul, SV Anisimov - Biochimie, 2013 - Elsevier
Mesenchymal stem cells have shown regenerative properties in many tissues. This feature
had originally been ascribed to their multipotency and thus their ability to differentiate into …
had originally been ascribed to their multipotency and thus their ability to differentiate into …
Mesenchymal stem cells: therapeutic mechanisms for stroke
Y Zhang, N Dong, H Hong, J Qi, S Zhang… - International Journal of …, 2022 - mdpi.com
Due to aging of the world's population, stroke has become increasingly prevalent, leading to
a rise in socioeconomic burden. In the recent past, stroke research and treatment have …
a rise in socioeconomic burden. In the recent past, stroke research and treatment have …
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