Aneurysms are localized pathological dilations of any vessel, and in arteries, a diameter of
1.5 times that of the normal artery is a generally accepted definition. Morphologically …

Aneurysmal disease of the aorta, defined as a focal dilation exceeding 150% of the normal
arterial diameter [1], is a potentially fatal disease occurring with increasing frequency in our …

Abdominal aortic aneurysm (AAA) is a complex multifactorial disease with life-threatening
implications. Aneurysms typically have no signs or symptoms, and rupture of AAA has a high …

Extensive studies into the etiology of aortic aneurysm disease have focused on the
characteristic and unique inflammatory infiltration and elaboration of products of …

We now know our past concepts of AAA pathogenesis to be oversimplified and inaccurate.
In fact, the metabolic activity of the aneurysm wall is markedly increased in comparison with …

BACKGROUND: Clinical presentation, maximal aortic diameter (Dmax), and growth rate are
considered important clinical characteristics of the abdominal aortic aneurysm (AAA) …

Objectives. The objective of this study was to investigate the changes in histology and
proteolysis and the role of apoptosis in the development of peripheral artery aneurysms …

Abdominal Aortic Aneurysms (AAAs) are associated with advanced age, male gender,
cigarette smoking, atherosclerosis, hypertension, and genetic predisposition. Basic research …

Figure. Cerebral aneurysm (CA) formation and rupture. Aneurysm formation is initiated by
hemodynamically triggered endothelial dysfunction. An inflammatory response implicating …

The development of a saccular (nondissecting) aortic aneurysm follows the destruction of
the connective tissue in the media, in particular the elastic lamellae. The vessel wall is then …