Site specificity of aneurysmal disease
PE Norman, JT Powell - Circulation, 2010 - Am Heart Assoc
Aneurysms are localized pathological dilations of any vessel, and in arteries, a diameter of
1.5 times that of the normal artery is a generally accepted definition. Morphologically …
1.5 times that of the normal artery is a generally accepted definition. Morphologically …
The pathobiology of aortic aneurysms
JJ Alexander - Journal of surgical research, 2004 - Elsevier
Aneurysmal disease of the aorta, defined as a focal dilation exceeding 150% of the normal
arterial diameter [1], is a potentially fatal disease occurring with increasing frequency in our …
arterial diameter [1], is a potentially fatal disease occurring with increasing frequency in our …
Basic research studies to understand aneurysm disease.
Abdominal aortic aneurysm (AAA) is a complex multifactorial disease with life-threatening
implications. Aneurysms typically have no signs or symptoms, and rupture of AAA has a high …
implications. Aneurysms typically have no signs or symptoms, and rupture of AAA has a high …
Digging in the “soil” of the aorta to understand the growth of abdominal aortic aneurysms
JA Curci - Vascular, 2009 - journals.sagepub.com
Extensive studies into the etiology of aortic aneurysm disease have focused on the
characteristic and unique inflammatory infiltration and elaboration of products of …
characteristic and unique inflammatory infiltration and elaboration of products of …
Pathogenesis of aneurysms.
BG Halloran, BT Baxter - Seminars in vascular surgery, 1995 - europepmc.org
We now know our past concepts of AAA pathogenesis to be oversimplified and inaccurate.
In fact, the metabolic activity of the aneurysm wall is markedly increased in comparison with …
In fact, the metabolic activity of the aneurysm wall is markedly increased in comparison with …
Histological features of human abdominal aortic aneurysm are not related to clinical characteristics
FA Hellenthal, ILA Geenen, JAW Teijink… - Cardiovascular …, 2009 - Elsevier
BACKGROUND: Clinical presentation, maximal aortic diameter (Dmax), and growth rate are
considered important clinical characteristics of the abdominal aortic aneurysm (AAA) …
considered important clinical characteristics of the abdominal aortic aneurysm (AAA) …
Initial steps in the unifying theory of the pathogenesis of artery aneurysms
T Jacob, E Ascher, A Hingorani, Y Gunduz… - Journal of Surgical …, 2001 - Elsevier
Objectives. The objective of this study was to investigate the changes in histology and
proteolysis and the role of apoptosis in the development of peripheral artery aneurysms …
proteolysis and the role of apoptosis in the development of peripheral artery aneurysms …
[HTML][HTML] Challenges and opportunities in abdominal aortic aneurysm research
M Wassef, GR Upchurch Jr, H Kuivaniemi… - Journal of vascular …, 2007 - Elsevier
Abdominal Aortic Aneurysms (AAAs) are associated with advanced age, male gender,
cigarette smoking, atherosclerosis, hypertension, and genetic predisposition. Basic research …
cigarette smoking, atherosclerosis, hypertension, and genetic predisposition. Basic research …
Review of cerebral aneurysm formation, growth, and rupture
Figure. Cerebral aneurysm (CA) formation and rupture. Aneurysm formation is initiated by
hemodynamically triggered endothelial dysfunction. An inflammatory response implicating …
hemodynamically triggered endothelial dysfunction. An inflammatory response implicating …
Aortic aneurysm formation: lessons from human studies and experimental models
MJ Davies - Circulation, 1998 - Am Heart Assoc
The development of a saccular (nondissecting) aortic aneurysm follows the destruction of
the connective tissue in the media, in particular the elastic lamellae. The vessel wall is then …
the connective tissue in the media, in particular the elastic lamellae. The vessel wall is then …