[HTML][HTML] Overview of OxLDL and its impact on cardiovascular health: focus on atherosclerosis

AV Poznyak, NG Nikiforov, AM Markin… - Frontiers in …, 2021 - frontiersin.org
Cardiovascular pathologies maintain the leading position in mortality worldwide.
Atherosclerosis is a chronic disease that can result in a variety of serious complications …

[HTML][HTML] Mechanisms of oxidized LDL-mediated endothelial dysfunction and its consequences for the development of atherosclerosis

H Jiang, Y Zhou, SM Nabavi, A Sahebkar… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is an immuno-metabolic disease involving chronic inflammation, oxidative
stress, epigenetics, and metabolic dysfunction. There is compelling evidence suggesting …

Circulating oxidized LDL: a biomarker and a pathogenic factor

Y Ishigaki, Y Oka, H Katagiri - Current opinion in lipidology, 2009 - journals.lww.com
Circulating oxidized LDL: a biomarker and a pathogenic facto... : Current Opinion in
Lipidology Circulating oxidized LDL: a biomarker and a pathogenic factor : Current Opinion …

Oxidized LDL, LOX-1 and atherosclerosis

S Mitra, T Goyal, JL Mehta - Cardiovascular drugs and therapy, 2011 - Springer
An elevated level of low density lipoprotein (LDL) cholesterol constitutes a major risk factor
for genesis of atherosclerosis. Ox-LDL plays a more important role in the genesis and …

Impact of oxidized low density lipoprotein on vascular cells

J Galle, T Hansen-Hagge, C Wanner, S Seibold - Atherosclerosis, 2006 - Elsevier
Oxidized LDL (OxLDL) is a proatherogenic lipoprotein, accumulating in the vascular wall
and contributing to the pathogenesis of vascular dysfunction early in the development of …

Oxidized low-density lipoprotein and atherosclerosis implications in antioxidant therapy

S Mitra, A Deshmukh, R Sachdeva, J Lu… - The American journal of …, 2011 - Elsevier
Abstract Low-density lipoprotein (LDL)-cholesterol is important for cellular function, but in
high concentrations, it can lead to atheroma formation. Over the past several decades, it has …

Circulating oxidized LDL is associated with subclinical atherosclerosis development and inflammatory cytokines (AIR Study)

J Hulthe, B Fagerberg - Arteriosclerosis, thrombosis, and vascular …, 2002 - Am Heart Assoc
Objective—Circulating oxidized LDL (Ox-LDL) is associated with clinical manifestations of
atherosclerosis. However, no previous study has examined the relationship between …

[HTML][HTML] Modulation of nitric oxide synthases by oxidized LDLs: role in vascular inflammation and atherosclerosis development

M Gliozzi, M Scicchitano, F Bosco, V Musolino… - International journal of …, 2019 - mdpi.com
The maintenance of physiological levels of nitric oxide (NO) produced by eNOS represents a
key element for vascular endothelial homeostasis. On the other hand, NO overproduction …

Oxidative modification of LDL: its pathological role in atherosclerosis

H Itabe - Clinical reviews in allergy & immunology, 2009 - Springer
Oxidized low-density lipoprotein (OxLDL) is a well-known risk marker for cardiovascular
diseases. OxLDL has shown a variety of proatherogenic properties in experiments …

Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases

A Trpkovic, I Resanovic, J Stanimirovic… - Critical reviews in …, 2015 - Taylor & Francis
Atherosclerosis is a life-long illness that begins with risk factors, which in turn contribute to
the development of subclinical disease, followed by the establishment of overt …