Pituitary adenomas (PAs) can be unpredictable and aggressive tumors. No reliable markers
of their biological behavior have been found. Here, a proteomic analysis was applied to …

Background Histidine triad nucleotide binding protein 1 (HINT1) is a haplo-insufficient tumor
suppressor gene that plays a significant role in cell proliferation and survival. However, to …

To study the clinical significance of HINT2 expression in patients with HCC. We investigated
HINT2 mRNA expression in tumors and adjacent non-tumor hepatic tissues from 106 HCC …

HINT1, a member of the evolutionary highly conserved HIT protein superfamily, is
ubiquitously expressed in diverse species including mammalian tissues. Accumulating …

Histidine triad nucleotide‑binding protein (HINT) belongs to the histidine triad protein family.
Recent studies have demonstrated that HINT1 and HINT2 both play a pivotal role in cancer …

Background New evidence suggests that histidine triad nucleotide-binding protein 1 (Hint1)
exerts a tumor suppressor effect in various human tumors, such as colorectal cancer and …

The histidine triad nucleotide binding protein1 (Hint1) belongs to the first branch of the HIT
superfamily. Hint1 catalyses the process of hydrolysis of the PN bond in AMP-lysine, AMP …

Simple Summary Pituitary adenomas are highly prevalent intracranial neoplasms that can
be locally invasive in up to half of cases. Consequently, using the term “PitNETs”(pituitary …

Introduction Pituitary neuroendocrine tumours (PitNETs) are common accounting for 10 to
25% of all intracranial tumours. This project describes the feasibility of developing a novel …

Histidine triad nucleotide-binding protein 1 (HINT1) is a member of a superfamily of histidine
triad proteins named by the conserved nucleotide-binding motif histidine-x-histidine-x …