[HTML][HTML] Aromatic Bromination Abolishes Deficits in Visuospatial Learning Induced by MDMA (“Ecstasy”) in Rats While Preserving the Ability to Increase LTP in the …

P Sáez-Briones, B Palma, H Burgos, R Barra… - International Journal of …, 2023 - mdpi.com
It has recently been demonstrated that aromatic bromination at C (2) abolishes all typical
psychomotor, and some key prosocial effects of the entactogen MDMA in rats. Nevertheless …

MDMA enhances hippocampal-dependent learning and memory under restrictive conditions, and modifies hippocampal spine density

S Abad, A Fole, N Del Olmo, D Pubill, M Pallàs… - …, 2014 - Springer
Objectives Addictive drugs produce forms of structural plasticity in the nucleus accumbens
and prefrontal cortex. The aim of this study was to investigate the impact of chronic MDMA …

Effects of MDMA on the induction of synaptic plasticity in visual cortex and hippocampus

C Rozas, M Encina, M Reyes-Parada, F Pancetti… - J Physiol P, 2005 - researchgate.net
The amphetamine analog 3, 4-methylenedioxymethamphetamine (MDMA), has become
popular as a “recreational” drug. Cognitive impairment has been related to the use of MDMA …

The intriguing effects of ecstasy (MDMA) on cognitive function in mice subjected to a minimal traumatic brain injury (mTBI)

S Edut, V Rubovitch, S Schreiber, CG Pick - Psychopharmacology, 2011 - Springer
Rationale The use of ecstasy (MDMA) among young adults has dramatically increased over
the years. Since MDMA may impair the users' driving ability, the risk of being involved in a …

Enhanced hippocampal long-term potentiation following repeated MDMA treatment in Dark–Agouti rats

R Morini, B Mlinar, G Baccini, R Corradetti - European …, 2011 - Elsevier
In rats and primates,(±) 3, 4-Methylenedioxymethamphetamine (MDMA, ecstasy) produces
both long-lasting damage to serotonergic axons and memory impairment. Our objective was …

A Multimodal Preclinical Assessment of MDMA in Female and Male Rats: Prohedonic, Cognition Disruptive, and Prosocial Effects

AS Adam, KS LaMalfa, Y Razavi, SJ Kohut… - Psychedelic …, 2024 - liebertpub.com
Background: Frontline antidepressants such as selective serotonin reuptake inhibitors
(SSRIs) leave many patients with unmet treatment needs. Moreover, even when SSRIs …

MDMA (“ecstasy”) impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats

A Arias-Cavieres, C Rozas, M Reyes-Parada… - Neuroscience …, 2010 - Elsevier
3, 4-Methylenedioxymethamphetamine (MDMA), an important recreational psychostimulant
drug, was examined for its ability to alter visuo-spatial learning and synaptic plasticity …

[HTML][HTML] Acute MDMA and nicotine co-administration: behavioral effects and oxidative stress processes in mice

B Budzynska, A Wnorowski, K Kaszubska… - Frontiers in behavioral …, 2018 - frontiersin.org
3, 4-Methylenedioxy-methylamphetamine (MDMA), a synthetic substance commonly known
as ecstasy, is a worldwide recreational drug of abuse. As MDMA and nicotine activate the …

[HTML][HTML] Behavioral and stereological analysis of the effects of intermittent feeding diet on the orally administrated MDMA (“ecstasy”) in mice

Z Ebrahimian, Z Karimi, MJ Khoshnoud… - Innovations in Clinical …, 2017 - ncbi.nlm.nih.gov
Background: 3, 4-methylenedioxy-methamphetamine or MDMA (also known as “ecstasy” or
“molly”) is a commonly abused drug that affects behavior and can lead to neuronal damage …

Lamotrigine, a mood stabilizer, may have beneficial effects on memory acquisition and retrieval in mice

IK Celikyurt, G Ulak, O Mutlu, FY Akar, F Erden… - Life sciences, 2012 - Elsevier
AIMS: The aim of this study was to investigate the effects of a mood stabilizer lamotrigine
(LMG) on learning and memory processes using Morris water maze (MWM), modified …