Inflammation modulation is currently considered a promising therapeutic strategy to
counteract the burden of cardiovascular disease. Amentoflavone (AME) is a natural …

Inflammation is the primary pathological process of myocardial ischemia/reperfusion injury
(MI/RI). 7-Hydroxyflavone (HF), a natural flavonoid with a variety of bioactivities, plays a …

Eupatilin, a pharmacologically active flavone derived from the Artemisia plant species, has
been reported to have anti-oxidant, anti-inflammatory, anti-allergic, and neuroprotective …

Doxorubicin (DOX) is an available chemotherapeutic drug for treating various tumors.
However, its effectiveness is limited by cardiotoxicity. Amentoflavone (AMF), a natural …

Background/Aims: Previous studies have demonstrated that Bauhinia championii flavone
(BCF) exhibits anti-oxidative, anti-hypoxic and anti-stress properties. This study was …

Background Doxorubicin (DOX) is a potent anticancer chemotherapeutic agent whose
clinical application is substantially constrained by its cardiotoxicity. The pathophysiology of …

Apocynum venetum, a Chinese medicinal herb, is reported to be neuroprotective. However,
whether Apocynum venetum leaf extract (AVLE) protects against ischemic myocardium …

Myocardial ischemia/reperfusion injury (I/RI) frequently incurs in acute myocardial infarction
with high morbidity and mortality worldwide and is characterized with cardiomyocyte …

The present study investigates the potential signal pathway of acacetin in cardioprotection
against ischemia/reperfusion injury using an in vitro hypoxia/reoxygenation model in primary …

Substantial evidence suggests that overproduction of reactive oxygen species (ROS) and its
associated oxidative stress and inflammatory responses play a crucial role in the …