Risk Factors for Ovarian Cancer by BRCA Status: A Collaborative Case-Only Analysis

K Gersekowski, R Na, K Alsop, R Delahunty… - … Biomarkers & Prevention, 2024 - AACR
Background: Women with an inherited pathogenic variant in BRCA 1 or BRCA 2 have a
greatly increased risk of developing ovarian cancer, but the importance of behavioral factors …

Reproductive and Hormonal Factors, and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Results from the International BRCA1/2 Carrier Cohort …

AC Antoniou, M Rookus, N Andrieu, R Brohet… - … Biomarkers & Prevention, 2009 - AACR
Background: Several reproductive and hormonal factors are known to be associated with
ovarian cancer risk in the general population, including parity and oral contraceptive (OC) …

Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation

YY Xia, J Gronwald, B Karlan, J Lubinski… - Gynecologic …, 2022 - Elsevier
Abstract Background BRCA1 and BRCA2 (BRCA) mutation carriers face a high lifetime risk
of developing ovarian cancer. Oral contraceptives are protective in this population; however …

Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutation carriers (United States)

F Modugno, R Moslehi, RB Ness, DB Nelson… - Cancer Causes & …, 2003 - Springer
Objective: To determine whether oral contraceptive (OC) use, childbearing, breastfeeding
and tubal ligation differ between ovarian cancer cases with and without a BRCA1/2 …

Germline BRCA variants, lifestyle and ovarian cancer survival

K Gersekowski, R Delahunty, K Alsop, EL Goode… - Gynecologic …, 2022 - Elsevier
Objective Women with ovarian cancer who have a pathogenic germline variant in BRCA1 or
BRCA2 (BRCA) have been shown to have better 5-year survival after diagnosis than women …

Relation of Contraceptive and Reproductive History to Ovarian Cancer Risk in Carriers and Noncarriers of BRCA1 Gene Mutations

V McGuire, A Felberg, M Mills, KL Ostrow… - American journal of …, 2004 - academic.oup.com
In the general population, ovarian cancer risk is inversely associated with oral contraceptive
use, tubal ligation, and childbearing. Among carriers of BRCA1 gene mutations, the data are …

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

SJ Ramus, AC Antoniou, KB Kuchenbaecker… - Human …, 2012 - Wiley Online Library
Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and
ovarian cancer. A genome‐wide association study (GWAS) identified six alleles associated …

Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study

JR McLaughlin, HA Risch, J Lubinski, P Moller… - The lancet …, 2007 - thelancet.com
Background Several of the known risk factors for ovarian cancer are thought to act through
their effects on ovulation and the menstrual cycle, such as parity, breastfeeding, and use of …

Better Life Expectancy in Women with BRCA2 Compared with BRCA1 Mutations Is Attributable to Lower Frequency and Later Onset of Ovarian Cancer

LM Byrd, A Shenton, ER Maher, E Woodward… - … Biomarkers & Prevention, 2008 - AACR
Purpose: No formal assessment of life expectancy in women with BRCA1 and BRCA2
mutations in these genes has been reported previously. We have evaluated life expectancy …

The association between cancer family history and ovarian cancer risk in BRCA1/2 mutation carriers: can it be explained by the mutation position?

N Teixeira, A van der Hout, JC Oosterwijk… - European Journal of …, 2018 - nature.com
This observational study aimed to investigate whether the reported association between
family history (FH) of breast cancer (BC) or ovarian cancer (OC) and OC risks in BRCA1/2 …