Maternal-effect genes (MEGs) play an important role in maintaining the survival and
development of mammalian embryos at the cleavage stage after fertilization. Despite long …

Abstract Purpose Nucleoporin 37 (NUP37) has been reported to activate the YAP-TEAD
signaling, which is crucial for early embryo development. However, whether NUP37 is …

Abstract Nucleoporin 50 kDa (NUP50), a component of the nuclear pore complex, is highly
expressed in male germ cells, but its role in germ cells is largely unknown. In this study, we …

Nucleoporins (Nups) are a family of proteins best known as the constituent building blocks of
nuclear pore complexes (NPCs), membrane-embedded channels that mediate nuclear …

Abstract Nucleoporin p62 (Nup62) localizes in the central channel of nuclear pore
complexes (NPCs) and regulates nuclear pore permeability and nucleocytoplasmic …

Cervical cancer is a prevalent and devastating malignancy in females worldwide.
Nucleoporin 93 (Nup93), a member of the nuclear pore complex, plays an important role in …

In brief Proper early embryonic development in mammals relies on precise cellular signaling
pathways. This study reveals that NSUN5 is crucial for the regulation of the Hippo pathway …

OBJECTIVE: The nucleoporin NUP98 is a component of the nuclear pore complex that
regulates nucleocytoplasmic trafficking. It has been characterized in acute myeloid leukemia …

The nuclear pore complex (NPC) mediates the transport of macromolecules between the
nucleus and cytoplasm. Recent evidence indicates that structural nucleoporins, the building …

The nuclear pore complex (NPC) regulates nuclear transport of RNA and proteins. Also,
nucleoporins regulate chromatin organization and gene expression. However, the role of …