Oligonucleotide (ON) therapeutics are molecular target agents composed of chemically
synthesized DNA or RNA molecules capable of inhibiting gene expression or protein …

Nanoparticle-based delivery systems have emerged as promising tools in oligonucleotide
therapeutics, facilitating precise and targeted delivery to address several disease conditions …

Therapeutic oligonucleotides (TOs) represent one of the most promising drug candidates in
the targeted cancer treatment due to their high specificity and capability of modulating …

Oligonucleotides (ONs) comprise a rapidly growing class of therapeutics. In recent years, the
list of FDA-approved ON therapies has rapidly expanded. ONs are small (15–30 bp) …

Nanoparticles with oligonucleotides bound to the outside or incorporated into the matrix can
be used for gene editing or to modulate gene expression in the CNS. These nanocarriers …

Importance of the field: Cancer is frequently caused by altered protein expression.
Oligonucleotides (ONs) are short synthetic nucleic acid fragments, able to selectively correct …

Oligonucleotide-based drugs are currently being developed for many different applications,
and in every case these drugs allow specific recognition of a cellular target that can be DNA …

Introduction: The use of aptamers, antisense technology and RNA interference has allowed
nucleic acids to be considered as promising alternatives to classical drugs. However …

The rapid development of nanotechnology has a great influence on the fields of biology,
physiology, and medicine. Over recent years, nanoparticles have been widely presented as …

Hematological malignancies are a group of diseases characterized by clonal proliferation of
blood-forming cells. Malignant blood cells are classified as myeloid or lymphoid cells …