[HTML][HTML] Investigating the causal relationships between excess adiposity and cardiometabolic health in men and women

PM Mutie, H Pomares-Milan, N Atabaki-Pasdar… - Diabetologia, 2023 - Springer
Aims/hypothesis Excess adiposity is differentially associated with increased risk of
cardiometabolic disease in men and women, according to observational studies. Causal …

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

S Hägg, T Fall, A Ploner, R Mägi… - International journal …, 2015 - academic.oup.com
Background: Adiposity, as indicated by body mass index (BMI), has been associated with
risk of cardiovascular diseases in epidemiological studies. We aimed to investigate if these …

Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies

MS Kim, WJ Kim, AV Khera, JY Kim… - European heart …, 2021 - academic.oup.com
Aims The aim of this study was to investigate the causal relationship and evidence of an
association between increased adiposity and the risk of incident cardiovascular disease …

Age-and sex-specific causal effects of adiposity on cardiovascular risk factors

T Fall, S Hägg, A Ploner, R Mägi, K Fischer… - Diabetes, 2015 - Am Diabetes Assoc
Observational studies have reported different effects of adiposity on cardiovascular risk
factors across age and sex. Since cardiovascular risk factors are enriched in obese …

[HTML][HTML] The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

BG Nordestgaard, TM Palmer, M Benn, J Zacho… - PLoS …, 2012 - journals.plos.org
Background Adiposity, assessed as elevated body mass index (BMI), is associated with
increased risk of ischemic heart disease (IHD); however, whether this is causal is unknown …

Type 2 diabetes and adiposity induce different lipid profile disorders: a mendelian randomization analysis

N Wang, J Cheng, Z Ning, Y Chen… - The Journal of …, 2018 - academic.oup.com
Context Type 2 diabetes and obesity often coexist, so it is difficult to judge whether diabetes
or obesity induce certain types of hyperlipidemia due to mutual confounds and reverse …

[HTML][HTML] The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

T Fall, S Hägg, R Maegi, A Ploner, K Fischer… - PLoS …, 2013 - journals.plos.org
Background The association between adiposity and cardiometabolic traits is well known
from epidemiological studies. Whilst the causal relationship is clear for some of these traits …

[HTML][HTML] Assessing causal estimates of the association of obesity-related traits with coronary artery disease using a Mendelian randomization approach

X Zhang, WQ Lv, B Qiu, LJ Zhang, J Qin, FJ Tang… - Scientific reports, 2018 - nature.com
Obesity-related traits have been associated with coronary artery disease (CAD) in
observational studies, but these associations may be biased by confounding factors and …

The impact of confounding on the associations of different adiposity measures with the incidence of cardiovascular disease: a cohort study of 296 535 adults of white …

S Iliodromiti, CA Celis-Morales, DM Lyall… - European heart …, 2018 - academic.oup.com
Aims The data regarding the associations of body mass index (BMI) with cardiovascular
(CVD) risk, especially for those at the low categories of BMI, are conflicting. The aim of our …

[HTML][HTML] Associations between body fat variability and later onset of cardiovascular disease risk factors

Y Saito, O Takahashi, H Arioka, D Kobayashi - PloS one, 2017 - journals.plos.org
Objective There is current debate regarding whether body weight variability is associated
with cardiovascular events. Recently, high body fat percentage (BF%) has been shown to be …