Interleukin-6 is an important pro-inflammatory cytokine strongly linked to the most burdened
exocrine pancreatic diseases including acute pancreatitis, chronic pancreatitis and …

Pancreatic cancer has attracted a great deal of attention owing to the poor outcome,
increasing prevalence in the last years and delay diagnosis. Known as a complex disease, it …

Background Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with a
poor prognosis and little treatment options. The development and progression of the disease …

Pancreatic cancer, one of the deadliest human malignancies, is almost invariably associated
with the presence of an oncogenic form of Kras. Mice expressing oncogenic Kras in the …

Pancreatic cancer has one of the poorest prognoses of all malignancies, with little
improvement in clinical outcome over the past 40 years. Pancreatic ductal adenocarcinoma …

Background While inflammation is associated with pancreatic cancer, the underlying
mechanisms leading to cancer initiation are still being delineated. Eosinophils may promote …

Objectives High serum level of interleukin 6 (IL-6) is associated with high degree of tumor
progression and systemic weakness. Anti–IL-6 therapy possibly improves the deterioration …

Background/Aims Recent experimental studies have suggested that various cytokines may
be important players in the development and progression of pancreatic cancer. However …

Originally described as an interferon (IFN)-γ-inducing factor, interleukin (IL)-18 has been
reported to be involved in Th1 and Th2 immune responses, as well as in activation of NK …

Abstract Background and Aim: Cytokines play an important role in the pathogenesis of acute
pancreatitis (AP). The aim of the present paper was to study the profile of anti‐and …