Formalin-fixed and paraffin-embedded (FFPE) tissue specimens are the gold standard for
histological examination, and they provide valuable molecular information in tissue-based …

We present the first analytical approach to demonstrate the in situ imaging of metabolites
from formalin‐fixed, paraffin‐embedded (FFPE) human tissue samples. Using high …

Matrix‐assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is a
molecular imaging technology uniquely capable of untargeted measurement of proteins …

Significant progress in instrumentation and sample preparation approaches have recently
expanded the potential of MALDI imaging mass spectrometry to the analysis of …

Archived formalin-fixed paraffin-embedded (FFPE) tissue collections represent a valuable
informational resource for proteomic studies. Multiple FFPE core biopsies can be assembled …

Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MALDI
MSI) has become a powerful tool with a high potential relevance for the analysis of …

Molecular imaging of tissue by MALDI mass spectrometry is a powerful tool for visualizing
the spatial distribution of constituent analytes with high molecular specificity. Although the …

Understanding the spatial distribution of bioactive small molecules is indispensable for
elucidating their biological or pharmaceutical roles. Mass spectrometry imaging (MSI) …

The molecular complexity of biological tissue and the spatial and temporal variation in the
biological processes involved in human disease requires new technologies and new …

Recent advancements in Matrix Assisted Laser Desorption/Ionisation (MALDI) Mass
Spectrometry Imaging (MSI) technology have enabled the analysis of formalin-fixed paraffin …