Under cell stress, global protein synthesis is inhibited to preserve energy. One mechanism is
to sequester and silence mRNAs in ribonucleoprotein complexes known as stress granules …

The Y-box binding protein 1 (YB-1) is a member of the cold shock domain (CSD) protein
family and is recognized as an oncogenic factor in several solid tumors. By binding to RNA …

Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD)
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …

Y-box–binding protein 1 (YB-1) is a multifunctional RNA binding protein involved in virtually
every step of RNA metabolism. However, the functions and mechanisms of YB-1 in one of …

Stress granules (SGs) are membraneless organelles that form in eukaryotic cells after stress
exposure [1](reviewed in [2–4]). Following translation inhibition, polysome disassembly …

Stress granules (SGs) are ribonucleoprotein aggregates that form in response to stress
conditions. The regulation of SG dynamics is not fully understood. Permanent pathological …

YB-1 is a broad-specificity RNA-binding protein that is involved in regulation of mRNA
transcription, splicing, translation, and stability. In both germinal and somatic cells, YB-1 and …

Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …

Metastatic dissemination is the leading cause of death in cancer patients, which is
particularly evident for high-risk sarcomas such as Ewing sarcoma, osteosarcoma, and …

The Y-box binding protein 1 (YB-1) is upregulated in many human malignancies including
glioblastoma (GBM). It is also essential for normal brain development, suggesting that YB-1 …