Clinical significance of the BRAFV600E mutation in multifocal papillary thyroid carcinoma in Korea

HY Ahn, YJ Chung, BS Kim, KH Kang, JW Seok… - Surgery, 2014 - Elsevier
Background We examined the frequency of the BRAF V600E mutation and compared the
clinicopathologic features based on the BRAF V600E mutation status in multifocal papillary …

BRAFV600E status and clinical characteristics in solitary and multiple papillary thyroid carcinoma: experience of 512 cases at a clinical center in China

X Zheng, T Xia, L Lin, S Gao, Y Lee, Y Yu, S Wei… - World Journal of …, 2012 - Springer
Background Papillary thyroid carcinoma (PTC) is one of the most frequent endocrine
malignancies. In most cases, it often presents as multifocal tumor. It has been reported that …

[HTML][HTML] BRAF V600E mutation co-existing with oncogenic mutations is associated with aggressive clinicopathologic features and poor prognosis in papillary thyroid …

N Bandoh, T Goto, Y Kato, A Kubota, S Sakaue… - Asian Journal of …, 2024 - Elsevier
Background The aim of this study was to evaluate the correlation among mutations in cancer-
related genes, clinicopathologic features, and clinical outcome in classical papillary thyroid …

Progression of solitary and multifocal papillary thyroid carcinoma—a retrospective study of 368 patients

Z Xiang-qian, W Chen, XU Meng, YU Yang… - Chinese medical …, 2012 - journals.lww.com
Background Papillary thyroid carcinoma (PTC) represents one of the most frequent
endocrine malignancies. Several factors have been found to be involved in determining the …

Analysis of differential BRAFV600E mutational status in multifocal papillary thyroid carcinoma: Evidence of independent clonal origin in distinct tumor foci

SY Park, YJ Park, YJ Lee, HS Lee, SH Choi, G Choe… - Cancer, 2006 - Wiley Online Library
BACKGROUND. Papillary thyroid cancers often occur as multiple foci. Multifocal cancers
have been considered to have a poor prognosis because they are thought to be the …

Clinical implication of the BRAFV600E mutation in papillary thyroid carcinoma

YS Kim, JS Kim, JS Bae, WC Park - World Journal of Surgical Oncology, 2013 - Springer
Abstract Background The BRAF V600E mutation is the most common genetic alteration in
papillary thyroid carcinoma (PTC). In recent studies, the BRAF V600E mutation has been …

BRAF V600E gene mutation is associated with bilateral malignancy of papillary thyroid cancer

Z Liu, T Lv, C Xie, Z Di - The American Journal of the Medical Sciences, 2018 - Elsevier
Background Papillary thyroid cancer (PTC) is the most prevalent type of thyroid cancer,
which is the most common type of endocrine malignancy. Stratification and personalized …

BRAF Testing in Multifocal Papillary Thyroid Carcinoma

HZ Kimbrell, AB Sholl, S Ratnayaka… - BioMed research …, 2015 - Wiley Online Library
Background. BRAF V600E mutation is associated with poor prognosis in patients with
papillary thyroid carcinoma (PTC). PTC is often multifocal, and there are no guidelines on …

[HTML][HTML] BRAF V600E mutation correlates with aggressive clinico-pathological features but does not influence tumor recurrence in papillary thyroid carcinoma—10 …

N Tabriz, J Grone, V Uslar, A Tannapfel, D Weyhe - Gland Surgery, 2020 - ncbi.nlm.nih.gov
Background BRAF V600E mutation is common in papillary thyroid carcinoma (PTC) but its
prognostic value and influence on tumor recurrence is controversial. We investigated if …

[HTML][HTML] A case of multifocal papillary thyroid carcinoma consisting of one encapsulated follicular variant with BRAF K601E mutation and three conventional types with …

WY Kim, YS Ko, TS Hwang, HS Han… - Korean journal of …, 2013 - ncbi.nlm.nih.gov
Multifocal papillary thyroid carcinoma (mPTC) comprises about 20-30% of PTC. In mPTC,
individual tumor foci can be identical or frequently composed of different histological types …