COL14A1 promotes self-renewal of human liver cancer stem cells through activation of ERK signaling
R Kong, H Liu, Y Shi, Q Man, S Liu - Journal of Bio-X Research, 2021 - spj.science.org
Objective: Liver cancer stem cells (CSCs) are the culprits of hepatocellular carcinoma
metastasis and recurrence. Only by eliminating tumor stem cells can malignant tumors be …
metastasis and recurrence. Only by eliminating tumor stem cells can malignant tumors be …
[HTML][HTML] MicroRNA-302a/d inhibits the self-renewal capability and cell cycle entry of liver cancer stem cells by targeting the E2F7/AKT axis
YS Ma, ZW Lv, F Yu, ZY Chang, XL Cong… - Journal of Experimental …, 2018 - Springer
Background There is increasing evidence that liver cancer stem cells (LCSCs) contribute to
hepatocellular carcinoma (HCC) initiation and progression. MicroRNA (miRNA) plays a …
hepatocellular carcinoma (HCC) initiation and progression. MicroRNA (miRNA) plays a …
MicroRNA‐28‐5p regulates liver cancer stem cell expansion via IGF‐1 pathway
Q Xia, T Han, P Yang, R Wang, H Li… - Stem Cells …, 2019 - Wiley Online Library
Background. MicroRNAs (miRNAs) play a critical role in the regulation of cancer stem cells
(CSCs). However, the role of miRNAs in liver CSCs has not been fully elucidated. Methods …
(CSCs). However, the role of miRNAs in liver CSCs has not been fully elucidated. Methods …
MicroRNA-6838-5p suppresses the self-renewal and metastasis of human liver cancer stem cells through downregulating CBX4 expression and inactivating ERK …
Z Dou, F Lu, J Hu, H Wang, B Li, X Li - Biological Chemistry, 2023 - degruyter.com
Hepatocellular carcinoma (HCC) is the most common primary human liver malignancy with
high mortality. Liver cancer stem cells (CSCs) have been demonstrated to contribute to the …
high mortality. Liver cancer stem cells (CSCs) have been demonstrated to contribute to the …
miR-613 inhibits liver cancer stem cell expansion by regulating SOX9 pathway
B Li, D Liu, P Yang, HY Li, D Wang - Gene, 2019 - Elsevier
Liver cancer stem cells (CSCs) contribute to tumorigenesis, progression, drug resistance
and recurrence of hepatocellular carcinoma (HCC). However, the underlying mechanism for …
and recurrence of hepatocellular carcinoma (HCC). However, the underlying mechanism for …
A novel regulatory loop miR-101/ANXA2/EGR1 mediates malignant characteristics of liver cancer stem cells
S Ma, J Cheng, H Wang, N Ding, F Zhou, R Ji… - …, 2021 - academic.oup.com
Increasing evidence suggests that liver cancer stem cells (LCSCs) are the cellular
determinants that promote tumor recurrence and metastases. Aberrantly expressed miRNAs …
determinants that promote tumor recurrence and metastases. Aberrantly expressed miRNAs …
Regulatory role of miRNA-1246 and Wnt/β-catenin pathway interaction in CD133+ liver cancer stem cells-driven hepatocellular carcinoma
Hepatocellular carcinoma (HCC), the main type of liver cancer in human, is one of the most
prevalent and deadly malignancies in the world. Despite advances in therapy, prognosis …
prevalent and deadly malignancies in the world. Despite advances in therapy, prognosis …
COL4A1, negatively regulated by XPD and miR-29a-3p, promotes cell proliferation, migration, invasion and epithelial–mesenchymal transition in liver cancer cells
H Zhang, Y Wang, H Ding - Clinical and Translational Oncology, 2021 - Springer
Objective Collagen type IV alpha 1 (COL4A1) exerts tumor-promoting functions in several
tumors. However, its role in liver cancer remains not fully understood. Hence, this study aims …
tumors. However, its role in liver cancer remains not fully understood. Hence, this study aims …
[HTML][HTML] MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway
Z Zheng, J Liu, Z Yang, L Wu, H Xie, C Jiang, B Lin… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The decrease of microRNA-452 (miR-452) in gliomas promoted stem-like features and
tumorigenesis. However, the role of miR-452, especially in regulating cancer stem cells …
tumorigenesis. However, the role of miR-452, especially in regulating cancer stem cells …
miR-219 regulates liver cancer stem cell expansion via E-cadherin pathway
A Si, L Wang, K Miao, R Zhang, H Ji, Z Lei, Z Cheng… - Cell Cycle, 2019 - Taylor & Francis
Liver cancer stem cells contribute to tumorigenesis, progression, recurrence and drug
resistance of hepatocellular carcinoma (HCC). However, the underlying mechanism for the …
resistance of hepatocellular carcinoma (HCC). However, the underlying mechanism for the …
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