Chromosomal abnormalities, consisting of numerical and structural chromosome
abnormalities, are a common characteristic of cancer. Numerical chromosome …

This review gives an account of chromosomal aberrations in cancer cells. Such
abnormalities have typically been associated with hematologic cancers, but recent work has …

Chromosomal changes have been detected in virtually all human tumortypes, and many of
these chromosomal abnormalities have been established asvaluable diagnostic and …

Chromosomal abnormalities are a defining feature of solid tumors. Such cytogenetic
alterations are mainly classified into structural chromosomal aberrations and copy number …

Genetic instability, which includes both numerical and structural chromosomal
abnormalities, is a hallmark of cancer. Whereas the structural chromosome rearrangements …

The pace of discoveries into the biologic basis of chromosomal instability in cancer cells is
quickening and the various causes, previously thought to be unrelated, are being found to …

Aberrations in the number and structure of chromosomes are a common feature of cells from
solid tumours. In this brief review, I summarize the evidence that there is a causal …

Chromosomal aberrations during cell division represent one of the first recognized features
of human cancer cells, and modern detection methods have revealed the pervasiveness of …

Cancer cells are typically characterized by complex karyotypes including both structural and
numerical changes, with aneuploidy being a ubiquitous feature. It is becoming increasingly …

Cytogenetic investigations of neoplastic cells during the past 25 years have revealed more
than 600 acquired, recurrent, balanced chromosome rearrangements, and it has been …