Nearly all psychiatric disorders present with circadian disruption, such as abnormalities in
the timing of the sleep-wake cycle, core body temperature rhythms, and melatonin and …

Exciting new results have increasingly utilized objective and validated instruments to
measure the circadian system in experimental studies. Since 2011, treatment research has …

Objective Several lines of evidence support a relationship between circadian rhythms
disruption in the onset, course, and maintenance of mental disorders. Despite the study of …

This work is supported by Swiss National Research Foundation Grants, the Velux
Foundation, the European Union 6th Framework Programme grant EUCLOCK, and the …

Highlights•Sleep and circadian rhythm disruption (SCRD) is a common comorbidity in
psychiatric disorders.•Common mechanisms may underlie SCRD and psychiatric disease …

Disturbances in circadian timing can have profound effects on the quality and quantity of
sleep as well as the expression and severity of neuropsychiatric and other medical …

Altered behavioral rhythms are a fundamental diagnostic feature of mood disorders. Patients
report worse subjective sleep and objective measures confirm this, implicating a role for …

Circadian rhythms are near 24-h cycles in a number of physiological and behavioural
parameters and the underpinning circadian timing systems is one of the key homeostatic …

Circadian rhythm alterations have been implicated in multiple neuropsychiatric disorders,
particularly those of sleep, addiction, anxiety, and mood. Circadian rhythms are known to be …

This paper reviews some of the compelling evidence of disrupted circadian rhythms in
individuals with mood disorders (major depressive disorder, seasonal affective disorder, and …