Type I and type II interferons (IFN) are central to both combating virus infection and
modulating the antiviral immune response. Indeed, an absence of either the receptor for type …

Type I interferon (IFN), as its name implies,'interferes' with virus replication by activating
numerous genes. Further, virus-induced type I IFN regulates the magnitude and functions of …

Interferons (IFNs) are cytokines that are important for immune responses, particularly to
intracellular pathogens. They are divided into two structurally and functionally distinct types …

Type I interferons (IFNs) are a family of cytokines specialized to coordinate immunity to
viruses and other intracellular infections. In the past several years, many of the receptors …

Type I interferons (IFNs) are pro-inflammatory cytokines that are rapidly induced in different
cell types during viral infections. The consequences of type I IFN signalling include direct …

Defense against bacterial infections requires activation of the immune response as well as
timely reestablishment of tissue and immune homeostasis. Instauration of homeostasis is …

Type I interferons (IFN-I) have long been heralded as key contributors to effective antiviral
responses. More widely understood in the context of acute viral infection, the role of this …

Type I interferons (IFNs) are pleiotropic cytokines well recognized for their role in the
induction of a potent antiviral gene program essential for host defense against viruses. They …

Although the role of type I interferon (IFN) in the protection against viral infections has been
known and studied for decades, its role in other immunologically relevant scenarios …

Type I interferons (IFN-α/β) and the more recently identified type III IFNs (IFN-λ) function as
the first line of defense against virus infection and regulate the development of both innate …