Antimicrobial resistance is presently one of the greatest threats to public health. The
excessive and indiscriminate use of antibiotics imposes a continuous selective pressure that …

Antibiotic resistance is a public health issue of global dimensions with a significant impact
on morbidity, mortality and healthcare-associated costs. The problem has recently been …

As the prevalence of antimicrobial resistance genes is increasing in microbes, we are facing
the return of the pre-antibiotic era. Consecutively, the number of studies concerning …

Antibiotic resistance in bacteria has emerged as a global challenge over the past 90 years,
compromising our ability to effectively treat infections. There has been a dramatic increase in …

The increase and spread of multidrug-resistant (MDR) Gram-negative bacteria, including
Enterobacteriaceae, Pseudomonas and Acinetobacter species, have become major …

Background Development of drug resistance in bacteria causes antibiotic therapies to be
less effective and more costly. Moreover, our understanding of the process remains …

The use of high-throughput sequencing technologies and bioinformatic tools has greatly
transformed microbial genome research. With the help of sophisticated computational tools …

The field of antibiotic drug discovery and the monitoring of new antibiotic resistance
elements have yet to fully exploit the power of the genome revolution. Despite the fact that …

Identification of the nucleotide sequences encoding antibiotic resistance elements and
determination of their association with antibiotic resistance are critical to improve …

The spread of antibiotic resistance poses a critical challenge worldwide. Contaminated
environments can become reservoirs, spreading antibiotic-resistant bacteria and genetic …