Ligand‐installed nanocarriers toward precision therapy
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …
[HTML][HTML] Progress and challenges towards targeted delivery of cancer therapeutics
Targeted delivery approaches for cancer therapeutics have shown a steep rise over the past
few decades. However, compared to the plethora of successful pre-clinical studies, only 15 …
few decades. However, compared to the plethora of successful pre-clinical studies, only 15 …
Extracellularly activated nanocarriers: a new paradigm of tumor targeted drug delivery
E Gullotti, Y Yeo - Molecular pharmaceutics, 2009 - ACS Publications
One of the main goals of nanomedicine is to develop a nanocarrier that can selectively
deliver anticancer drugs to the targeted tumors. Extensive efforts have resulted in several …
deliver anticancer drugs to the targeted tumors. Extensive efforts have resulted in several …
Actively targeted nanocarriers for drug delivery to cancer cells
S Biffi, R Voltan, B Bortot, G Zauli… - Expert opinion on drug …, 2019 - Taylor & Francis
Introduction: Progressive breakthroughs in nanomedicine have been instrumental for the
clinical translation of actively targeted drug-delivery approaches. Besides storing large …
clinical translation of actively targeted drug-delivery approaches. Besides storing large …
Development of highly efficient nanocarrier-mediated delivery approaches for cancer therapy
Nanocarriers (NCs) are a group of nano-sized vehicles devised to deliver drugs to targeted
malignant tissues or organs that provide remarkably improved targeting efficiency and …
malignant tissues or organs that provide remarkably improved targeting efficiency and …
Recent advances in targeted nanomedicine as promising antitumor therapeutics
Highlights•Nanocarriers with the ability to target tumors are being increasingly explored.•
Nanomedicine aid in maintaining a balance between efficacy and toxicity.•Recent advances …
Nanomedicine aid in maintaining a balance between efficacy and toxicity.•Recent advances …
Engineering the assemblies of biomaterial nanocarriers for delivery of multiple theranostic agents with enhanced antitumor efficacy.
The rapid development of nanotechnology holds great promise for revolutionizing the
current landscape of tumor drug delivery. However, one of the biggest challenges is …
current landscape of tumor drug delivery. However, one of the biggest challenges is …
Challenges in design of translational nanocarriers
Cancer drug delivery achieving high therapeutic efficacy and low side effects requires a
nanocarrier to tightly retain the drug, efficiently reach the tumor, then quickly enter the tumor …
nanocarrier to tightly retain the drug, efficiently reach the tumor, then quickly enter the tumor …
[HTML][HTML] Tumour-targeted nanomedicines: principles and practice
Drug targeting systems are nanometre-sized carrier materials designed for improving the
biodistribution of systemically applied (chemo) therapeutics. Various different tumour …
biodistribution of systemically applied (chemo) therapeutics. Various different tumour …
Ligand-based targeted therapy for cancer tissue
M Das, C Mohanty, SK Sahoo - Expert opinion on drug delivery, 2009 - Taylor & Francis
Background: Limited accessibility of drugs to the tumor tissues, the requirement of high
doses, intolerable cytotoxicity, the development of multiple drug resistance and non-specific …
doses, intolerable cytotoxicity, the development of multiple drug resistance and non-specific …