Brain capillary endothelial cells express a variety of nucleotide receptors, but differences
have been reported between culture models. This study reports examination of nucleotide …

1 A dual‐wavelength microfluorimetric method using Fura‐2 as calcium indicator was
applied to cells from an immortalized cell line of rat brain microvascular endothelial cells …

1 The blood‐brain barrier is formed by capillary endothelial cells and is regulated by cell‐
surface receptors, such as the G protein‐coupled P2Y receptors for nucleotides. Here we …

This study examined the intracellular regulation of signal transduction initiated by activation
of the P2Y2 purinoceptor in a cultured rat brain microvascular endothelial cell line (RBE4) …

1 Purinoceptor agonist‐induced currents in untreated (proliferating) and lipopolysaccharide
(LPS; 100 ng ml− 1)‐treated (non‐proliferating) rat microglial cells in culture were recorded …

In primary unpassaged rat brain capillary endothelial cell cultures (RBECs), using reverse‐
transcriptase PCR with primers specific for P2Y receptor subtypes, we detected mRNA for …

A P2Y (nucleotide) receptor activity in a clonal population (B10) of rat brain capillary
endothelial cells is coupled to inhibition of adenylyl cyclase and has functional similarities to …

The action of adenine and uracyl nucleotides on rat brain capillary endothelial cells was
investigated. ATP, UTP, and adenosine 5'-O-(3-thiotrisphosphate) activated phospholipase …

The response of bovine aortic endothelial cells to adenosine 5'-triphosphate (ATP) is
mediated by both P2y and nucleotide/P2u receptors. In order to determine which form of the …

Extracellular adenosine triphosphate (ATP) plays an important role in the regulation of
endothelial function. However, its receptors and their signal-transduction pathways in major …