Lung imaging—two dimensional gamma scintigraphy, SPECT, CT and PET

J Conway - Advanced drug delivery reviews, 2012 - Elsevier
This review will cover the principles of imaging the deposition of inhaled drugs and some of
the state-of-the art imaging techniques being used today. Aerosol deposition can be imaged …

Imaging techniques for assessing drug delivery in man

SP Newman, IR Wilding - Pharmaceutical science & technology today, 1999 - Elsevier
In vivo imaging technologies have a vital role to play in the pharmaceutical development
process. Gamma scintigraphy, comprising two-dimensional 'planar'imaging, is used widely …

Challenges in assessing regional distribution of inhaled drug in the human lungs

S Newman, J Fleming - Expert Opinion on Drug Delivery, 2011 - Taylor & Francis
Introduction: Both the total amount of drug deposited in the lungs (whole lung deposition)
and the amount deposited in different lung regions (regional lung deposition) are potentially …

The co-imaging of gamma camera measurements of aerosol deposition and respiratory anatomy

J Conway, J Fleming, M Bennett… - Journal of aerosol …, 2013 - liebertpub.com
The use of gamma camera imaging following the inhalation of a radiolabel has been widely
used by researchers to investigate the fate of inhaled aerosols. The application of two …

Radionuclide imaging technologies and their use in evaluating asthma drug deposition in the lungs

SP Newman, GR Pitcairn, PH Hirst, L Rankin - Advanced drug delivery …, 2003 - Elsevier
Whole lung and regional lung deposition of inhaled asthma drugs in the lungs can be
quantified using either two-dimensional or three-dimensional radionuclide imaging …

Radionuclide scanning, respiratory physiology, and pharmacokinetics

GC Smaldone - Journal of Aerosol Medicine, 2001 - liebertpub.com
THE CURRENT ISSUE OF THE Journal of Aerosol Medicine contains articles devoted to
gamma camera imaging. The gamma camera has proved invaluable in the advancement of …

Nuclear medicine imaging methods as novel tools in the assessment of pulmonary drug disposition

S Mairinger, I Hernández-Lozano… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Drugs for the treatment of respiratory diseases are commonly administered by
oral inhalation. Yet surprisingly little is known about the pulmonary pharmacokinetics of …

Imaging in aerosol medicine

TE Corcoran - Respiratory Care, 2015 - rc.rcjournal.com
Imaging techniques have been used extensively to study the delivery of inhaled
medications. Deposition scintigraphy involves the quantification of deposited aerosol dose …

The use of combined single photon emission computed tomography and X-ray computed tomography to assess the fate of inhaled aerosol

J Fleming, J Conway, C Majoral… - Journal of aerosol …, 2011 - liebertpub.com
Background: Gamma camera imaging is widely used to assess pulmonary aerosol
deposition. Conventional planar imaging provides limited information on its regional …

Measuring total and regional lung deposition using inhaled radiotracers

MB Dolovich - Journal of Aerosol Medicine, 2001 - liebertpub.com
The delivery of an inhaled drug to the lungs can be measured by adding a γ-emitting
radiotracer to the formulation and using two-dimensional planar imaging or three …