Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial
Treatment protocols for pediatric diabetic ketoacidosis (DKA) vary considerably among
centers in the USA and worldwide. The optimal protocol for intravenous (IV) fluid …
centers in the USA and worldwide. The optimal protocol for intravenous (IV) fluid …
Clinical trial of fluid infusion rates for pediatric diabetic ketoacidosis
N Kuppermann, S Ghetti, JE Schunk… - … England Journal of …, 2018 - Mass Medical Soc
Background Diabetic ketoacidosis in children may cause brain injuries ranging from mild to
severe. Whether intravenous fluids contribute to these injuries has been debated for …
severe. Whether intravenous fluids contribute to these injuries has been debated for …
Emergency medicine myths: cerebral edema in pediatric diabetic ketoacidosis and intravenous fluids
Background Pediatric diabetic ketoacidosis (DKA) is a disease associated with several
complications that can be severe. One complication includes cerebral edema (CE), and …
complications that can be severe. One complication includes cerebral edema (CE), and …
Fluid management in pediatric patients with DKA and rates of suspected clinical cerebral edema
DS Hsia, SG Tarai, A Alimi, JA Coss‐Bu… - Pediatric …, 2015 - Wiley Online Library
Objective To compare outcomes of diabetic ketoacidosis (DKA) 6 yrs before and 6 yrs after
changing rehydration fluids from ½ normal saline to Lactated Ringer's and decreasing the …
changing rehydration fluids from ½ normal saline to Lactated Ringer's and decreasing the …
Low morbidity and mortality in children with diabetic ketoacidosis treated with isotonic fluids
PC White, BA Dickson - The Journal of pediatrics, 2013 - Elsevier
Objective To assess current rates of complications of diabetic ketoacidosis (DKA),
particularly cerebral edema, in a large tertiary-care pediatric hospital with a consistent …
particularly cerebral edema, in a large tertiary-care pediatric hospital with a consistent …
Fluid therapy for pediatric patients with diabetic ketoacidosis: current perspectives
M Jayashree, V Williams, R Iyer - Diabetes, Metabolic Syndrome …, 2019 - Taylor & Francis
Diabetic ketoacidosis (DKA) is a preventable life-threatening complication of type 1
diabetes. Fluids form a crucial component of DKA therapy, goals being the restoration of …
diabetes. Fluids form a crucial component of DKA therapy, goals being the restoration of …
Diabetic ketoacidosis fluid management in children: systematic review and meta-analyses
AA Hamud, K Mudawi, A Shamekh, A Kadri… - Archives of Disease in …, 2022 - adc.bmj.com
Importance Diabetic ketoacidosis (DKA) is a serious complication of type 1 diabetes mellitus,
which may lead to significant morbidity and mortality. Objectives To compare the safety and …
which may lead to significant morbidity and mortality. Objectives To compare the safety and …
Evidence-based emergency medicine/critically appraised topic. Is fluid therapy associated with cerebral edema in children with diabetic ketoacidosis?
J Hom, R Sinert - Annals of Emergency Medicine, 2008 - europepmc.org
Study objective Diabetic ketoacidosis is the most common cause of morbidity and mortality
in children with type I diabetes mellitus, and cerebral edema is the leading cause of pediatric …
in children with type I diabetes mellitus, and cerebral edema is the leading cause of pediatric …
An 18‐yr prospective study of pediatric diabetic ketoacidosis: an approach to minimizing the risk of brain herniation during treatment
I Fiordalisi, WE Novotny, D Holbert, L Finberg… - Pediatric …, 2007 - Wiley Online Library
Background: During the late 1900s, raised intracranial pressure (ICP) during treatment of
pediatric diabetic ketoacidosis (DKA) surfaced as the most important cause of morbidity and …
pediatric diabetic ketoacidosis (DKA) surfaced as the most important cause of morbidity and …
Serum sodium concentration and mental status in children with diabetic ketoacidosis
OBJECTIVES Diabetic ketoacidosis (DKA) is typically characterized by low or low-normal
serum sodium concentrations, which rise as hyperglycemia resolves. In retrospective …
serum sodium concentrations, which rise as hyperglycemia resolves. In retrospective …
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