This paper reports findings of the “Focus on Controversial Areas” Working Party of the Italian
Senonetwork, which was set up to improve the care of breast cancer patients. After …

Hypothesis The best therapeutic approach to the involved or proximal surgical margins has
not been defined yet; surgical margins status can influence the local relapse of disease in …

Inadequate surgical margins represent a high risk for adverse clinical outcome in breast-
conserving therapy (BCT) for early-stage breast cancer. The majority of studies report …

Margins in breast conserving surgery (BCS) have been a long standing subject debate. This
largely arises from the absence of a consensus on what constitutes an adequate margin …

Breast cancer is the most common tumor affecting women worldwide. Breast-conserving
therapy (BCT) followed by irradiation nowadays is the treatment of choice for early-stage …

Background: Significant controversy exists regarding the appropriate minimum tumor-free
margin width for patients undergoing breast-conserving therapy. The SSO-ASTRO …

Objective To determine if margin involvement is associated with distant recurrence and to
determine the required margin to minimise both local recurrence and distant recurrence in …

Do surgical margins matter after mastectomy? A systematic review and meta-analysis -
European Journal of Cancer Skip to Main Content Advertisement European Journal of Cancer …

Objective Breast-conserving surgery has become the preferred treatment for early breast
cancer. Yet the question of what constitutes a 'safe margin', in terms of impact on patient …

Breast conserving surgery and mastectomy are equivalent for overall survival. However, the
rate of local recurrence is higher for breast conserving surgery. Several predictive factors for …