Mechanisms of antitumor invasion and metastasis of the marine fungal derivative epi-aszonalenin A in HT1080 cells

Y Liu, L Lin, H Zheng, YL He, Y Li, C Zhou, P Hong… - Marine Drugs, 2023 - mdpi.com
Epi-aszonalenin A (EAA) is an alkaloid that is isolated and purified from the secondary
metabolites of coral symbiotic fungi and has been shown to have good atherosclerotic …

Antiangiogenic activity of aeroplysinin‐1, a brominated compound isolated from a marine sponge

S Rodríguez-Nieto, M González-Iriarte… - The FASEB …, 2002 - Wiley Online Library
Aeroplysinin‐1, an antibacterial brominated compound produced by certain sponges, was
selected during a blind high‐throughput screening for new potential antiangiogenic …

Antimetastatic activity of polyphenol-rich extract of Ecklonia cava through the inhibition of the Akt pathway in A549 human lung cancer cells

H Lee, C Kang, E Jung, JS Kim, E Kim - Food chemistry, 2011 - Elsevier
An ethyl acetate extract (ECE) of a brown alga, Ecklonia cava, was examined for its anti-
metastatic effect, using A549 human lung carcinoma cells. ECE treatment significantly …

Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF …

Q Zhao, Z Liu, Y Xue, J Wang, H Li, Q Tang… - Journal of Zhejiang …, 2011 - Springer
Abstract Ds-echinoside A (DSEA), a non-sulfated triterpene glycoside, was isolated from the
sea cucumber Pearsonothuria graeffei. In vitro and in vivo investigations were conducted on …

Mechanism of two alkaloids isolated from coral endophytic fungus for suppressing angiogenesis in atherosclerotic plaque in HUVEC

Y Liu, Y Li, M Chen, Y Liu, J Liang, Y Zhang… - International …, 2022 - Elsevier
Atherosclerosis is a significant cause of many cardiovascular diseases. Oxidized low-density
lipoproteins (ox-LDL) are crucial in developing atherosclerosis. In this study, we researched …

Evaluation of Antiangiogenic Efficacy of Emilia sonchifolia (L.) DC on Tumor-Specific Neovessel Formation by Regulating MMPs, VEGF, and Proinflammatory …

GK Gilcy, G Kuttan - Integrative Cancer Therapies, 2016 - journals.sagepub.com
Formation of new blood vessels from preexisting vasculature is an indispensable process in
tumor initiation, invasion, and metastasis. Novel therapeutic approaches target endothelial …

Suppression of Migration and Invasion by 4‐Carbomethoxyl‐10‐Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on …

RY Fang, YW Liu, YG Goan, JJ Lin… - Advances in …, 2024 - Wiley Online Library
The primary reason for cancer‐related fatalities is metastasis. The compound 4‐
carbomethoxyl‐10‐epigyrosanoldie E, derived from the Sinularia sandensis soft coral …

Anti-Angiogenic Activity of Acalycixenolide E, a Novel Marine Natural Product from Acallycigorgia inermis

HJ Kwon, JH Kim, HJ Jung, YG Kwon… - … of microbiology and …, 2001 - koreascience.kr
Angiogenesis is known as a crucial process in the growth and spreading of tumor cells.
Accordingly, the effective inhibition of this process would appear to be a promising way to …

Toluhydroquinone, the secondary metabolite of marine algae symbiotic microorganism, inhibits angiogenesis in HUVECs

NH Kim, HI Jung, WS Choi, BW Son, YB Seo… - Biomedicine & …, 2015 - Elsevier
Angiogenesis, the growth of new blood vessels from the existing ones, occurs during
embryo development and wound healing. However, most malignant tumors require …

Anti-metastatic effect of deoxyelephantopin from Elephantopus scaber in A549 lung cancer cells in vitro

AK Farha, SR Dhanya, SN Mangalam… - Natural product …, 2015 - Taylor & Francis
In this study, we focused on the in vitro anti-metastatic effects of deoxyelephantopin (DOE), a
sesquiterpene lactone from Elephantopus scaber on lung cancer A549 cells. DOE …