新規の有用な化学物質の研究開発において, その安全性確保は最大の課題の
うちの一つであることはいうまでもない. 農薬, 医薬品等ではその上市までに急性, 亜急性, 慢性 …

The question may be asked why the National Cancer Institute, a research agency, should be
involved in studies on pesticides. In 1961, when the Etiology Area (formerly Field Studies) of …

JRP Cabral International Agency for Research on Cancer (IARC) Lyon, france What is a
pesticide? A pesticide is a substance ca Page 1 CARCINOGENICITY Of PESTICIDES JRP …

Skip the header click to show the menu Menu Cart Login Login/Register Institutional Access
Access Options Enter words / phrases / DOI / ISBN / keywords / authors / etc Search Advanced …

Short-term tests to detect genetic, chromosomal, or DNA damage are now required by
regulatory agencies for any new compound proposed for commercial production …

The carcinogenic potential of 5 pesticides was analyzed using a medium‐term multi‐organ
bioassay for carcinogenicity. Male F344 rats were initially treated with 3 known carcinogens …

Carcinogenicity data are presented for compounds used as pesticides which have been
evaluated in the IARC Monograph series. These pesticides have been both poorly and …

The sophistication, sensitivity, and the predicability of carcinogenesis bioassays using small
rodents is reviewed. Bioassays were conducted using both sexes of mice (B6C3F1 …

In reaching a regulatory decision on the use of pesticides with carcinogenic potential, it is of
great importance to investigate the extent of dermal exposure and absorption of a pesticide …

It has been debating about conducting and interpretating of 2-year rodent carcinogenicity
bioassay. Although some criticisms arising in usefulness, it has been still known that long …