Aconitase 1 (ACO1) links oxidative stress and iron accumulation in Parkinson's disease
(PD). ACO1 loses its aconitase activity and turns into iron regulatory protein 1 (IRP1) upon …

Aim: Iron dyshomeostasis is one of the primary causes of neuronal death in Alzheimer's
disease (AD). Huperzine A (HupA), a natural inhibitor of acetylcholinesterase (AChE), is a …

Parkinson's disease (PD) is a neurodegenerative disease characterized by the gradual loss
of dopaminergic (DA) neurons in the substantia nigra (SN) and the formation of intracellular …

Increasing evidence indicates that disruption of normal iron homeostasis may contribute to
pathological development of Alzheimer's disease. Icariin, astragalus, and puerarin have …

Oxidative stress plays an important role in the pathophysiology of various neurologic
disorders. Allium cepa extract (ACE) and their main flavonoid component quercetin (QCT) …

Alzheimer's disease (AD) is a neurodegenerative brain disorder and the most common
cause of dementia. New treatments for AD are required due to its increasing prevalence in …

Lonchocarpine is a phenylpropanoid compound isolated from Abrus precatorius that has
anti-bacterial, anti-inflammatory, antiproliferative, and antiepileptic activities. In the present …

Oxidative stress is closely related to the pathogenesis of neurodegenerative disorders such
as Parkinson's disease and Alzheimer's disease. However, the underlying antioxidant …

Cadmium (Cd) is a highly neurotoxic environmental pollutant. Puerarin (Pur) is a natural
antioxidant isolated from Kudzu root that exhibits a powerful neuroprotective effect. Herein …

Abstract Aims: Ceruloplasmin (CP), a ferrous oxidase enzyme, plays an important role in
regulating iron metabolism and redox reactions. Previous studies showed that CP deficiency …