Background The antimicrobial resistance is a global problem, probably due to the
indiscriminate and irrational use of antibiotics, prescriptions for incorrect medicines or …

This article critically evaluates the main in vitro and in vivo studies published which compare
generic with the original molecules, both those administered orally and parenterally. The …

Background Demonstration of equivalent amounts of the same active pharmaceutical
ingredient (API) between generic and innovator products (pharmaceutical equivalence) is a …

Whereas infections caused by multidrug-resistant micro-organisms are increasing
worldwide, there are few new molecules, especially ones that are active against Gram …

Background One of the most critical problems about antimicrobial therapy is the increasing
resistance to antibiotics. Previous studies have shown that there is a direct relation between …

The emergence of bacterial resistance and the lack of new antibiotics in the pipeline
represent a public health priority. Maximizing the quality of antibiotic prescriptions is …

Objective To compile the results of investigations conducted in 84 centers throughout
Europe of the in vitro activity of meropenem and a standard set of comparators against some …

Objective: To investigate and compare the in vitro pharmacodynamics of three
carbapenems: imipenem, meropenem and BO-2727. Methods: The following studies were …

Objectives The efficacy and quality of generic antibacterial drug formulations are often
questioned by both healthcare specialists and patients. Therefore, the present study …

Abstract The Meropenem yearly Susceptibility test information Collection (MYSTIC)
programme is a global, longitudinal resistance surveillance network that monitors the activity …