Innate immune responses recognizing pathogen associated molecular patterns play
important roles in adaptive immunity. As such, ligands which mimic the conserved products …

There has been significant interest in the potential of cytosine–guanine (CpG) containing
oligodeoxynucleotides (ODN) as an immunotherapy for malignant, infectious and allergic …

Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs act as immune
adjuvants, accelerating and boosting antigen-specific immune responses. CpG motifs …

Synthetic oligodeoxynucleotides (ODN) containing CpG sequences are recognized as a
“danger” signal by the immune system of mammals. As a consequence, CpG ODN stimulate …

Unmethylated cytosine–guanine dinucleotide (CpG) motifs are potent stimulators of the host
immune response. Cellular recognition of CpG motifs occurs via Toll-like receptor 9 (TLR9) …

Synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs trigger cells
that express Toll-like receptor 9 (including human plasmacytoid dendritic cells and B cells) …

Synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs directly
stimulate human B cells and plasmacytoid dendritic cells (pDCs), thereby promoting the …

Synthetic oligodeoxynucleotides containing unmethylated CpG-dinucleotides (CpG-ODNs)
are immunostimulatory in a broad spectrum of species. Extensive studies provide evidence …

Cytosine–phosphorothioate–guanine oligodeoxynucleotides (CpG ODN) is a recent class of
immunostimulatory adjuvants that includes unmethylated CpG dinucleotide sequences …

Synthetic oligodeoxynucleotides containing unmethylated CpG motifs act as immune
adjuvants, accelerating and boosting antigen-specific antibody responses by up to 500-fold …