Human-induced pluripotent stem cells (hiPSCs) and CRISPR/Cas9 gene editing system
represent two instruments of basic and translational research, which both allow to acquire …

The development of the reprogramming technology led to generation of induced Pluripotent
Stem Cells (iPSC) from a variety of somatic cells. Ever since, fast growing knowledge of …

Genome editing of human pluripotent stem cells (hPSCs) with the CRISPR/Cas9 system has
the potential to revolutionize hPSC‐based disease modeling, drug screening, and …

Induced pluripotent stem cells (iPSCs) have become an essential research platform to study
different human diseases once being discovered by Dr. Shinya Yamanaka in 2006. Another …

It is extremely rare for a single experiment to be so impactful and timely that it shapes and
forecasts the experiments of the next decade. Here, we review how two such experiments …

Genome editing using the CRISPR/Cas9 system has rapidly established itself as an
essential tool in the genetic manipulation of many organisms, including human cell lines. Its …

CRISPR-Cas technology has revolutionized biological research and holds great therapeutic
potential. Here, we review CRISPR-Cas systems and their latest developments with an …

In order to expand the promise of regenerative medicine using allogeneic induced
pluripotent stem cells (iPSCs), precise and efficient genome editing of human leukocyte …

Human pluripotent stem cells (hPSCs) have potential applications in biological studies and
regenerative medicine. However, precise genome editing in hPSCs remains time …

Human pluripotent stem cells (hPSCs) have the potential to generate all adult cell types,
including rare or inaccessible human cell populations, thus providing a unique platform for …