Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer

M Sopo, M Anttila, K Hämäläinen, A Kivelä… - BMC cancer, 2019 - Springer
Background In many malignancies including ovarian cancer, different angiogenic factors
have been related to poor prognosis. However, data on their relations to each other or …

Explorative investigation of vascular endothelial growth factor receptor expression in primary ovarian cancer and its clinical relevance

P Wimberger, I Chebouti, S Kasimir-Bauer… - Gynecologic …, 2014 - Elsevier
Objectives The identification of novel molecular biomarkers, predicting outcome of ovarian
cancer, is highly desirable. Considering that angiogenesis is a critical factor for ascites …

[HTML][HTML] VEGF-C expression attributes the risk for lymphatic metastases to ovarian cancer patients

S Kuerti, L Oliveira-Ferrer, K Milde-Langosch… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Peritoneal dissemination and retroperitoneal lymph node involvement are main
routes for progression of epithelial ovarian cancer (EOC). Vascular endothelial growth factor …

Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma

N Nishida, H Yano, K Komai, T Nishida… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND The vascular endothelial growth factor (VEGF) family and VEGF receptors
(VEGFR) play an essential role in the angiogenesis of both pathologic and nonpathologic …

Vascular endothelial growth factor expression in ovarian cancer: a model for targeted use of novel therapies?

TJ Duncan, A Al-Attar, P Rolland, IV Scott, S Deen… - Clinical Cancer …, 2008 - AACR
Purpose: Angiogenesis has a vital role in tumor growth and metastasis, and vascular
endothelial growth factor (VEGF) represents a potent cytokine in this process. However, the …

Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas

M Ueda, YC Hung, Y Terai, K Kanda, M Kanemura… - Clinical cancer …, 2005 - AACR
Purpose: To investigate the biological correlation between vascular endothelial growth
factor (VEGF)-C expression and invasive phenotype in ovarian carcinomas. Experimental …

Serum vascular endothelial growth factor-A as a prognostic biomarker for epithelial ovarian cancer

H Komatsu, T Oishi, H Itamochi, M Shimada… - International Journal of …, 2017 - ijgc.bmj.com
Background Bevacizumab, which targets vascular endothelial growth factor (VEGF)-A, has
recently been proven to be effective for the treatment of epithelial ovarian cancer (EOC) …

Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer

H Sallinen, T Heikura, J Koponen, VM Kosma… - BMC cancer, 2014 - Springer
Background The aim of the study was to explore the serum levels of eight angiogenesis
biomarkers in patients with benign, borderline or malignant epithelial ovarian neoplasms …

VEGF, VEGFR‐1, VEGFR‐2, microvessel density and endothelial cell proliferation in tumours of the ovary

M Orre, PAW Rogers - International journal of cancer, 1999 - Wiley Online Library
VEGF is an angiogenic factor with potent endothelial cell (EC) proliferative actions. Our aim
was to investigate whether expression of VEGF and its receptors and EC proliferation differ …

Immunohistochemical expression of VEGF predicts response to platinum based chemotherapy in patients with epithelial ovarian cancer

GK Siddiqui, AB Maclean, K Elmasry, A Wong te Fong… - Angiogenesis, 2011 - Springer
Purpose For patients with epithelial ovarian cancer (EOC) cytoreduction, with a combination
of taxane and platinum, is the standard of care. Despite this, approximately 50% of patients …