Underlying vulnerabilities to the cytokine storm and adverse COVID-19 outcomes in the aging immune system
LS Nidadavolu, JD Walston - The Journals of Gerontology …, 2021 - academic.oup.com
Older adults are far more vulnerable to adverse health outcomes and mortality after
contracting COVID-19. There are likely multiple age-related biological, clinical, and …
contracting COVID-19. There are likely multiple age-related biological, clinical, and …
[HTML][HTML] SARS-CoV-2, COVID-19 and the aging immune system
JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …
particular risk for severe disease and death in older adults and in adults with age-related …
[HTML][HTML] Remodeling of the immune response with aging: immunosenescence and its potential impact on COVID-19 immune response
Elderly individuals are the most susceptible to an aggressive form of coronavirus disease
(COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed …
(COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed …
COVID-19 and crosstalk with the hallmarks of aging
Within the past several decades, the emergence of new viral diseases with severe health
complications and mortality is evidence of an age-dependent, compromised bodily response …
complications and mortality is evidence of an age-dependent, compromised bodily response …
[HTML][HTML] Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?
V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …
[HTML][HTML] Aging, inflammaging and immunosenescence as risk factors of severe COVID-19
AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …
[HTML][HTML] From aging to long COVID: exploring the convergence of immunosenescence, inflammaging, and autoimmunity
L Müller, S Di Benedetto - Frontiers in Immunology, 2023 - frontiersin.org
The process of aging is accompanied by a dynamic restructuring of the immune response, a
phenomenon known as immunosenescence. This mini-review navigates through the …
phenomenon known as immunosenescence. This mini-review navigates through the …
Aging in COVID-19: Vulnerability, immunity and intervention
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …
[HTML][HTML] A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome …
A Bektas, SH Schurman, C Franceschi, L Ferrucci - Immunity & Ageing, 2020 - Springer
A central clinical question as the world deals with the COVID-19 pandemic is what the long-
term sequelae for the millions of individuals will be who recover from the hyperinflammatory …
term sequelae for the millions of individuals will be who recover from the hyperinflammatory …
Role of aging and the immune response to respiratory viral infections: potential implications for COVID-19
J Chen, WJ Kelley, DR Goldstein - The Journal of Immunology, 2020 - journals.aai.org
Aging impairs immunity to promote diseases, especially respiratory viral infections. The
current COVID-19 pandemic, resulting from SARS-CoV-2, induces acute pneumonia, a …
current COVID-19 pandemic, resulting from SARS-CoV-2, induces acute pneumonia, a …