Somatic mutations are post-zygotic mutational event that leads to generation of two or more
genotypes within an individual. With the recent advances in genomic technologies, there is …

Mosaicism is the presence of two or more genomes in an individual derived from a single
zygote. Mosaicism may occur in germ cells (germline mosaicism), potentially causing …

Mosaicism—the existence of genetically distinct populations of cells in a particular organism—
is an important cause of genetic disease. Mosaicism can appear as de novo DNA mutations …

Nearly all of the genetic material among cells within an organism is identical. However,
single-nucleotide variants (SNVs), small insertions/deletions (indels), copy-number variants …

With the introduction of increasingly sensitive technologies for mutation detection such as
chromosomal microarrays and next‐generation sequencing, the importance of mosaicism …

Mosaicism refers to the occurrence of two or more genomes in an individual derived from a
single zygote. Germline mosaicism is a mutation that is limited to the gonads and can be …

Mosaicisms caused by postzygotic mutational events are of increasing interest because of
their potential association with various human diseases. Postzygotic somatic mutations have …

Although the idea that all cells in the body contain an identical genetic component
(genotype) may be a tempting one, the reality is that cells often differ genetically. Mosaicism …

Somatic mutations occur after the formation of the zygote, reflecting random mutations
during normal mitotic cell divisions of embryonic development, and are hence present in …

Somatic mosaicism refers to the occurrence of two genetically distinct populations of cells
within an individual, derived from a postzygotic mutation. In contrast to inherited mutations …