The brain and behavior are under energetic constraints, limited by mitochondrial energy
transformation capacity. However, the mitochondria-behavior relationship has not been …

Here we discuss the role of diverse environmental manipulations affecting cognition with
special regard to psychiatric conditions. We present evidence supporting a direct causal …

BACKGROUND: Although anxiety disorders are the most prevalent psychiatric disorders, no
molecular biomarkers exist for their premorbid diagnosis, accurate patient …

Background Emerging evidence points to a central role of mitochondria in psychiatric
disorders. However, little is known about the molecular players that regulate mitochondria in …

Stressful life events are major environmental risk factors for anxiety disorders, although not
all individuals exposed to stress develop clinical anxiety. The molecular mechanisms …

Mitochondrial dysfunction was highlighted as a crucial vulnerability factor for the
development of depression. However, systemic studies assessing stress-induced changes …

Sociality has profound evolutionary roots and is observed from unicellular organisms to
multicellular animals. In line with the view that social principles apply across levels of …

A central role of brain mitochondria in regulating and influencing social behaviour is
emerging. In addition to its important roles as the “powerhouses” of the cell, mitochondria …

Accumulating data highlight the contribution of brain mitochondria and bioenergetics to
psychiatric disorders and stress-related pathologies. Although anxiety has not received …

A revolution in our understanding of brain development, adult brain function, senescence,
and disease has emerged from the recognition of structural and functional plasticity within …